Staals RHJ - Search Results

1

Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus.

Staals RHJ, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJR, Yonekura K, van der Oost J, Shinkai A. Staals RHJ, et al. Mol Cell. 2013 Oct 10;52(1):135-145. doi: 10.1016/j.molcel.2013.09.013. Mol Cell. 2013. PMID: 24119403 Free PMC article.

2

Dis3-like 1: a novel exoribonuclease associated with the human exosome.

Staals RH, Bronkhorst AW, Schilders G, Slomovic S, Schuster G, Heck AJ, Raijmakers R, Pruijn GJ. Staals RH, et al. EMBO J. 2010 Jul 21;29(14):2358-67. doi: 10.1038/emboj.2010.122. Epub 2010 Jun 8. EMBO J. 2010. PMID: 20531389 Free PMC article.

3

CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.

Westra ER, van Erp PB, Künne T, Wong SP, Staals RH, Seegers CL, Bollen S, Jore MM, Semenova E, Severinov K, de Vos WM, Dame RT, de Vries R, Brouns SJ, van der Oost J. Westra ER, et al. Mol Cell. 2012 Jun 8;46(5):595-605. doi: 10.1016/j.molcel.2012.03.018. Epub 2012 Apr 19. Mol Cell. 2012. PMID: 22521689 Free PMC article.

4

The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity.

Westra ER, Swarts DC, Staals RH, Jore MM, Brouns SJ, van der Oost J. Westra ER, et al. Annu Rev Genet. 2012;46:311-39. doi: 10.1146/annurev-genet-110711-155447. Annu Rev Genet. 2012. PMID: 23145983 Review.

5

CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids.

Westra ER, Staals RH, Gort G, Høgh S, Neumann S, de la Cruz F, Fineran PC, Brouns SJ. Westra ER, et al. RNA Biol. 2013 May;10(5):749-61. doi: 10.4161/rna.24202. Epub 2013 Mar 27. RNA Biol. 2013. PMID: 23535265 Free PMC article.

6

The role of CRISPR-Cas systems in virulence of pathogenic bacteria.

Louwen R, Staals RH, Endtz HP, van Baarlen P, van der Oost J. Louwen R, et al. Microbiol Mol Biol Rev. 2014 Mar;78(1):74-88. doi: 10.1128/MMBR.00039-13. Microbiol Mol Biol Rev. 2014. PMID: 24600041 Free PMC article. Review.

7

Degenerate target sites mediate rapid primed CRISPR adaptation.

Fineran PC, Gerritzen MJ, Suárez-Diez M, Künne T, Boekhorst J, van Hijum SA, Staals RH, Brouns SJ. Fineran PC, et al. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1629-38. doi: 10.1073/pnas.1400071111. Epub 2014 Apr 7. Proc Natl Acad Sci U S A. 2014. PMID: 24711427 Free PMC article.

8

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.

Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, Urlaub H, Heck AJ, Nogales E, Doudna JA, Shinkai A, van der Oost J. Staals RH, et al. Mol Cell. 2014 Nov 20;56(4):518-30. doi: 10.1016/j.molcel.2014.10.005. Epub 2014 Nov 6. Mol Cell. 2014. PMID: 25457165 Free PMC article.

9

Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.

Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA. Taylor DW, et al. Science. 2015 May 1;348(6234):581-5. doi: 10.1126/science.aaa4535. Epub 2015 Apr 2. Science. 2015. PMID: 25837515 Free PMC article.

10

Analysis of protein-RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry.

Sharma K, Hrle A, Kramer K, Sachsenberg T, Staals RH, Randau L, Marchfelder A, van der Oost J, Kohlbacher O, Conti E, Urlaub H. Sharma K, et al. Methods. 2015 Nov 1;89:138-48. doi: 10.1016/j.ymeth.2015.06.005. Epub 2015 Jun 10. Methods. 2015. PMID: 26071038

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