Bebenek A - Search Results

1

A remote palm domain residue of RB69 DNA polymerase is critical for enzyme activity and influences the conformation of the active site.

Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. Jacewicz A, et al. Among authors: bebenek a. PLoS One. 2013 Oct 7;8(10):e76700. doi: 10.1371/journal.pone.0076700. eCollection 2013. PLoS One. 2013. PMID: 24116139 Free PMC article.

2

The roles of Tyr391 and Tyr619 in RB69 DNA polymerase replication fidelity.

Jacewicz A, Makiela K, Kierzek A, Drake JW, Bebenek A. Jacewicz A, et al. Among authors: bebenek a. J Mol Biol. 2007 Apr 20;368(1):18-29. doi: 10.1016/j.jmb.2007.01.067. Epub 2007 Feb 3. J Mol Biol. 2007. PMID: 17321543 Free PMC article.

3

Different behaviors in vivo of mutations in the beta hairpin loop of the DNA polymerases of the closely related phages T4 and RB69.

Trzemecka A, Płochocka D, Bebenek A. Trzemecka A, et al. Among authors: bebenek a. J Mol Biol. 2009 Jun 26;389(5):797-807. doi: 10.1016/j.jmb.2009.04.055. Epub 2009 May 3. J Mol Biol. 2009. PMID: 19409904

4

Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket.

Trzemecka A, Jacewicz A, Carver GT, Drake JW, Bebenek A. Trzemecka A, et al. Among authors: bebenek a. J Mol Biol. 2010 Dec 17;404(5):778-93. doi: 10.1016/j.jmb.2010.09.058. Epub 2010 Oct 13. J Mol Biol. 2010. PMID: 20950625 Free PMC article.

5

The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination.

Zhang H, Rhee C, Bebenek A, Drake JW, Wang J, Konigsberg W. Zhang H, et al. Among authors: bebenek a. Biochemistry. 2006 Feb 21;45(7):2211-20. doi: 10.1021/bi052099y. Biochemistry. 2006. PMID: 16475809 Free PMC article.

6

Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins.

Bebenek A, Carver GT, Dressman HK, Kadyrov FA, Haseman JK, Petrov V, Konigsberg WH, Karam JD, Drake JW. Bebenek A, et al. Genetics. 2002 Nov;162(3):1003-18. doi: 10.1093/genetics/162.3.1003. Genetics. 2002. PMID: 12454051 Free PMC article.

7

Processivity clamp gp45 and ssDNA-binding-protein gp32 modulate the fidelity of bacteriophage RB69 DNA polymerase in a sequence-specific manner, sometimes enhancing and sometimes compromising accuracy.

Bebenek A, Carver GT, Kadyrov FA, Kissling GE, Drake JW. Bebenek A, et al. Genetics. 2005 Apr;169(4):1815-24. doi: 10.1534/genetics.104.037630. Epub 2005 Feb 3. Genetics. 2005. PMID: 15695359 Free PMC article.

8

Fidelity of DNA replication-a matter of proofreading.

Bębenek A, Ziuzia-Graczyk I. Bębenek A, et al. Curr Genet. 2018 Oct;64(5):985-996. doi: 10.1007/s00294-018-0820-1. Epub 2018 Mar 2. Curr Genet. 2018. PMID: 29500597 Free PMC article. Review.

9

Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.

Bebenek A, Dressman HK, Carver GT, Ng S, Petrov V, Yang G, Konigsberg WH, Karam JD, Drake JW. Bebenek A, et al. J Biol Chem. 2001 Mar 30;276(13):10387-97. doi: 10.1074/jbc.M007707200. Epub 2000 Dec 22. J Biol Chem. 2001. PMID: 11133987 Free article.

10

Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex.

Garbacz M, Araki H, Flis K, Bebenek A, Zawada AE, Jonczyk P, Makiela-Dzbenska K, Fijalkowska IJ. Garbacz M, et al. Among authors: bebenek a. DNA Repair (Amst). 2015 May;29:23-35. doi: 10.1016/j.dnarep.2015.02.007. Epub 2015 Feb 16. DNA Repair (Amst). 2015. PMID: 25758782 Free article.

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