Guo Y - Search Results

1

Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase.

Wang C, Chang WC, Guo Y, Huang H, Peck SC, Pandelia ME, Lin GM, Liu HW, Krebs C, Bollinger JM Jr. Wang C, et al. Among authors: guo y. Science. 2013 Nov 22;342(6161):991-5. doi: 10.1126/science.1240373. Epub 2013 Oct 10. Science. 2013. PMID: 24114783 Free PMC article.

2

Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.

Chang WC, Guo Y, Wang C, Butch SE, Rosenzweig AC, Boal AK, Krebs C, Bollinger JM Jr. Chang WC, et al. Among authors: guo y. Science. 2014 Mar 7;343(6175):1140-4. doi: 10.1126/science.1248000. Science. 2014. PMID: 24604200 Free PMC article.

3

Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase.

Tamanaha E, Zhang B, Guo Y, Chang WC, Barr EW, Xing G, St Clair J, Ye S, Neese F, Bollinger JM Jr, Krebs C. Tamanaha E, et al. Among authors: guo y. J Am Chem Soc. 2016 Jul 20;138(28):8862-74. doi: 10.1021/jacs.6b04065. Epub 2016 Jul 5. J Am Chem Soc. 2016. PMID: 27193226 Free PMC article.

4

Mechanistic Investigation of a Non-Heme Iron Enzyme Catalyzed Epoxidation in (-)-4'-Methoxycyclopenin Biosynthesis.

Chang WC, Li J, Lee JL, Cronican AA, Guo Y. Chang WC, et al. Among authors: guo y. J Am Chem Soc. 2016 Aug 24;138(33):10390-3. doi: 10.1021/jacs.6b05400. Epub 2016 Aug 11. J Am Chem Soc. 2016. PMID: 27442345

5

O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase.

Peck SC, Wang C, Dassama LM, Zhang B, Guo Y, Rajakovich LJ, Bollinger JM Jr, Krebs C, van der Donk WA. Peck SC, et al. Among authors: guo y. J Am Chem Soc. 2017 Feb 8;139(5):2045-2052. doi: 10.1021/jacs.6b12147. Epub 2017 Jan 31. J Am Chem Soc. 2017. PMID: 28092705 Free PMC article.

6

Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation.

Liao HJ, Li J, Huang JL, Davidson M, Kurnikov I, Lin TS, Lee JL, Kurnikova M, Guo Y, Chan NL, Chang WC. Liao HJ, et al. Among authors: guo y. Angew Chem Int Ed Engl. 2018 Feb 12;57(7):1831-1835. doi: 10.1002/anie.201710567. Epub 2018 Jan 16. Angew Chem Int Ed Engl. 2018. PMID: 29314482

7

Mechanistic Investigation of Oxidative Decarboxylation Catalyzed by Two Iron(II)- and 2-Oxoglutarate-Dependent Enzymes.

Huang JL, Tang Y, Yu CP, Sanyal D, Jia X, Liu X, Guo Y, Chang WC. Huang JL, et al. Among authors: guo y. Biochemistry. 2018 Mar 27;57(12):1838-1841. doi: 10.1021/acs.biochem.8b00115. Epub 2018 Mar 13. Biochemistry. 2018. PMID: 29485871

8

Elucidating the Reaction Pathway of Decarboxylation-Assisted Olefination Catalyzed by a Mononuclear Non-Heme Iron Enzyme.

Yu CP, Tang Y, Cha L, Milikisiyants S, Smirnova TI, Smirnov AI, Guo Y, Chang WC. Yu CP, et al. Among authors: guo y. J Am Chem Soc. 2018 Nov 14;140(45):15190-15193. doi: 10.1021/jacs.8b10077. Epub 2018 Nov 5. J Am Chem Soc. 2018. PMID: 30376630 Free PMC article.

9

Repurposing Nonheme Iron Hydroxylases To Enable Catalytic Nitrile Installation through an Azido Group Assistance.

Davidson M, McNamee M, Fan R, Guo Y, Chang WC. Davidson M, et al. Among authors: guo y. J Am Chem Soc. 2019 Feb 27;141(8):3419-3423. doi: 10.1021/jacs.8b13906. Epub 2019 Feb 18. J Am Chem Soc. 2019. PMID: 30759343

10

Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases.

Chen TY, Chen J, Tang Y, Zhou J, Guo Y, Chang WC. Chen TY, et al. Among authors: guo y. Angew Chem Int Ed Engl. 2020 May 4;59(19):7367-7371. doi: 10.1002/anie.201914896. Epub 2020 Mar 10. Angew Chem Int Ed Engl. 2020. PMID: 32074393 Free PMC article.

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