Goc A - Search Results

1

Akt1 mediates α-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor.

Abdalla M, Goc A, Segar L, Somanath PR. Abdalla M, et al. Among authors: goc a. J Biol Chem. 2013 Nov 15;288(46):33483-93. doi: 10.1074/jbc.M113.504290. Epub 2013 Oct 8. J Biol Chem. 2013. PMID: 24106278 Free PMC article.

2

Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β₃ affinity modulation.

Goc A, Liu J, Byzova TV, Somanath PR. Goc A, et al. Br J Cancer. 2012 Aug 7;107(4):713-23. doi: 10.1038/bjc.2012.295. Epub 2012 Jul 5. Br J Cancer. 2012. PMID: 22767145 Free PMC article.

3

P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion.

Goc A, Al-Azayzih A, Abdalla M, Al-Husein B, Kavuri S, Lee J, Moses K, Somanath PR. Goc A, et al. J Biol Chem. 2013 Feb 1;288(5):3025-35. doi: 10.1074/jbc.M112.424770. Epub 2012 Dec 20. J Biol Chem. 2013. PMID: 23258534 Free PMC article.

4

p70 S6-kinase mediates the cooperation between Akt1 and Mek1 pathways in fibroblast-mediated extracellular matrix remodeling.

Goc A, Sabbineni H, Abdalla M, Somanath PR. Goc A, et al. Biochim Biophys Acta. 2015 Jul;1853(7):1626-35. doi: 10.1016/j.bbamcr.2015.03.016. Epub 2015 Apr 2. Biochim Biophys Acta. 2015. PMID: 25843685 Free PMC article.

5

TNFα induces inflammatory stress response in microvascular endothelial cells via Akt- and P38 MAP kinase-mediated thrombospondin-1 expression.

Fairaq A, Goc A, Artham S, Sabbineni H, Somanath PR. Fairaq A, et al. Among authors: goc a. Mol Cell Biochem. 2015 Aug;406(1-2):227-36. doi: 10.1007/s11010-015-2440-0. Epub 2015 May 12. Mol Cell Biochem. 2015. PMID: 25963668 Free PMC article.

6

Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.

Kochuparambil ST, Al-Husein B, Goc A, Soliman S, Somanath PR. Kochuparambil ST, et al. Among authors: goc a. J Pharmacol Exp Ther. 2011 Feb;336(2):496-505. doi: 10.1124/jpet.110.174870. Epub 2010 Nov 8. J Pharmacol Exp Ther. 2011. PMID: 21059805

7

PI3 kinase integrates Akt and MAP kinase signaling pathways in the regulation of prostate cancer.

Goc A, Al-Husein B, Kochuparambil ST, Liu J, Heston WW, Somanath PR. Goc A, et al. Int J Oncol. 2011 Jan;38(1):267-77. Int J Oncol. 2011. PMID: 21109949

8

TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR).

Goc A, Choudhary M, Byzova TV, Somanath PR. Goc A, et al. J Cell Physiol. 2011 Nov;226(11):3004-13. doi: 10.1002/jcp.22648. J Cell Physiol. 2011. PMID: 21302298 Free PMC article.

9

Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke.

Guan W, Somanath PR, Kozak A, Goc A, El-Remessy AB, Ergul A, Johnson MH, Alhusban A, Soliman S, Fagan SC. Guan W, et al. Among authors: goc a. PLoS One. 2011;6(9):e24551. doi: 10.1371/journal.pone.0024551. Epub 2011 Sep 1. PLoS One. 2011. PMID: 21912702 Free PMC article.

10

Rac1 activation driven by 14-3-3ζ dimerization promotes prostate cancer cell-matrix interactions, motility and transendothelial migration.

Goc A, Abdalla M, Al-Azayzih A, Somanath PR. Goc A, et al. PLoS One. 2012;7(7):e40594. doi: 10.1371/journal.pone.0040594. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808202 Free PMC article.

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