Mach RH - Search Results

1

Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer.

Zeng C, Vangveravong S, McDunn JE, Hawkins WG, Mach RH. Zeng C, et al. Among authors: mach rh. Br J Cancer. 2013 Oct 29;109(9):2368-77. doi: 10.1038/bjc.2013.593. Epub 2013 Oct 8. Br J Cancer. 2013. PMID: 24104966 Free PMC article.

2

Sigma-2 receptors as a biomarker of proliferation in solid tumours.

Wheeler KT, Wang LM, Wallen CA, Childers SR, Cline JM, Keng PC, Mach RH. Wheeler KT, et al. Among authors: mach rh. Br J Cancer. 2000 Mar;82(6):1223-32. doi: 10.1054/bjoc.1999.1067. Br J Cancer. 2000. PMID: 10735510 Free PMC article.

3

Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands.

Mach RH, Huang Y, Freeman RA, Wu L, Vangveravong S, Luedtke RR. Mach RH, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):195-202. doi: 10.1016/j.bmcl.2003.09.083. Bioorg Med Chem Lett. 2004. PMID: 14684327

4

Synthesis and characterization of selective dopamine D2 receptor antagonists.

Vangveravong S, McElveen E, Taylor M, Xu J, Tu Z, Luedtke RR, Mach RH. Vangveravong S, et al. Among authors: mach rh. Bioorg Med Chem. 2006 Feb 1;14(3):815-25. doi: 10.1016/j.bmc.2005.09.008. Epub 2005 Nov 8. Bioorg Med Chem. 2006. PMID: 16288878

5

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.

Xu J, Tu Z, Jones LA, Vangveravong S, Wheeler KT, Mach RH. Xu J, et al. Among authors: mach rh. Eur J Pharmacol. 2005 Nov 21;525(1-3):8-17. doi: 10.1016/j.ejphar.2005.09.063. Epub 2005 Nov 10. Eur J Pharmacol. 2005. PMID: 16289030

6

N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.

Chu W, Zhang J, Zeng C, Rothfuss J, Tu Z, Chu Y, Reichert DE, Welch MJ, Mach RH. Chu W, et al. Among authors: mach rh. J Med Chem. 2005 Dec 1;48(24):7637-47. doi: 10.1021/jm0506625. J Med Chem. 2005. PMID: 16302804

7

Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligands.

Vangveravong S, Xu J, Zeng C, Mach RH. Vangveravong S, et al. Among authors: mach rh. Bioorg Med Chem. 2006 Oct 15;14(20):6988-97. doi: 10.1016/j.bmc.2006.06.028. Epub 2006 Jul 11. Bioorg Med Chem. 2006. PMID: 16837201

8

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Among authors: mach rh. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

9

Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.

Tu Z, Xu J, Jones LA, Li S, Dumstorff C, Vangveravong S, Chen DL, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Among authors: mach rh. J Med Chem. 2007 Jul 12;50(14):3194-204. doi: 10.1021/jm0614883. Epub 2007 Jun 19. J Med Chem. 2007. PMID: 17579383

10

Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

Chu W, Rothfuss J, d'Avignon A, Zeng C, Zhou D, Hotchkiss RS, Mach RH. Chu W, et al. Among authors: mach rh. J Med Chem. 2007 Jul 26;50(15):3751-5. doi: 10.1021/jm070506t. Epub 2007 Jun 23. J Med Chem. 2007. PMID: 17585855

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