Hawkins WG - Search Results

1

Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer.

Zeng C, Vangveravong S, McDunn JE, Hawkins WG, Mach RH. Zeng C, et al. Among authors: hawkins wg. Br J Cancer. 2013 Oct 29;109(9):2368-77. doi: 10.1038/bjc.2013.593. Epub 2013 Oct 8. Br J Cancer. 2013. PMID: 24104966 Free PMC article.

2

TAT-Bim induces extensive apoptosis in cancer cells.

Kashiwagi H, McDunn JE, Goedegebuure PS, Gaffney MC, Chang K, Trinkaus K, Piwnica-Worms D, Hotchkiss RS, Hawkins WG. Kashiwagi H, et al. Among authors: hawkins wg. Ann Surg Oncol. 2007 May;14(5):1763-71. doi: 10.1245/s10434-006-9298-z. Epub 2007 Jan 6. Ann Surg Oncol. 2007. PMID: 17206479

3

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy.

Kashiwagi H, McDunn JE, Simon PO Jr, Goedegebuure PS, Xu J, Jones L, Chang K, Johnston F, Trinkaus K, Hotchkiss RS, Mach RH, Hawkins WG. Kashiwagi H, et al. Among authors: hawkins wg. Mol Cancer. 2007 Jul 15;6:48. doi: 10.1186/1476-4598-6-48. Mol Cancer. 2007. PMID: 17631687 Free PMC article.

4

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study.

Watanabe E, Muenzer JT, Hawkins WG, Davis CG, Dixon DJ, McDunn JE, Brackett DJ, Lerner MR, Swanson PE, Hotchkiss RS. Watanabe E, et al. Among authors: hawkins wg. Lab Invest. 2009 May;89(5):549-61. doi: 10.1038/labinvest.2009.8. Epub 2009 Feb 2. Lab Invest. 2009. PMID: 19188912 Free PMC article.

5

Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma.

Kashiwagi H, McDunn JE, Simon PO Jr, Goedegebuure PS, Vangveravong S, Chang K, Hotchkiss RS, Mach RH, Hawkins WG. Kashiwagi H, et al. Among authors: hawkins wg. J Transl Med. 2009 Mar 26;7:24. doi: 10.1186/1479-5876-7-24. J Transl Med. 2009. PMID: 19323815 Free PMC article.

6

Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma.

Simon PO Jr, McDunn JE, Kashiwagi H, Chang K, Goedegebuure PS, Hotchkiss RS, Hawkins WG. Simon PO Jr, et al. Among authors: hawkins wg. Int J Cancer. 2009 Aug 15;125(4):942-51. doi: 10.1002/ijc.24424. Int J Cancer. 2009. PMID: 19405118 Free PMC article.

7

A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing.

Spitzer D, McDunn JE, Plambeck-Suess S, Goedegebuure PS, Hotchkiss RS, Hawkins WG. Spitzer D, et al. Among authors: hawkins wg. Mol Cancer Ther. 2010 Jul;9(7):2142-51. doi: 10.1158/1535-7163.MCT-10-0225. Epub 2010 Jun 22. Mol Cancer Ther. 2010. PMID: 20571073 Free PMC article.

8

The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine.

Hornick JR, Xu J, Vangveravong S, Tu Z, Mitchem JB, Spitzer D, Goedegebuure P, Mach RH, Hawkins WG. Hornick JR, et al. Among authors: hawkins wg. Mol Cancer. 2010 Nov 22;9:298. doi: 10.1186/1476-4598-9-298. Mol Cancer. 2010. PMID: 21092190 Free PMC article.

9

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Xu J, et al. Among authors: hawkins wg. Nat Commun. 2011 Jul 5;2:380. doi: 10.1038/ncomms1386. Nat Commun. 2011. PMID: 21730960 Free PMC article.

10

Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling.

Spitzer D, Simon PO Jr, Kashiwagi H, Xu J, Zeng C, Vangveravong S, Zhou D, Chang K, McDunn JE, Hornick JR, Goedegebuure P, Hotchkiss RS, Mach RH, Hawkins WG. Spitzer D, et al. Among authors: hawkins wg. Cancer Res. 2012 Jan 1;72(1):201-9. doi: 10.1158/0008-5472.CAN-11-1354. Epub 2011 Nov 7. Cancer Res. 2012. PMID: 22065721 Free PMC article.

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