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Novel 6β-acylaminomorphinans with analgesic activity.
Váradi A, Hosztafi S, Le Rouzic V, Tóth G, Urai Á, Noszál B, Pasternak GW, Grinnell SG, Majumdar S. Váradi A, et al. Among authors: grinnell sg. Eur J Med Chem. 2013 Nov;69:786-9. doi: 10.1016/j.ejmech.2013.09.031. Epub 2013 Sep 22. Eur J Med Chem. 2013. PMID: 24103580 Free PMC article.
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.
Váradi A, Marrone GF, Palmer TC, Narayan A, Szabó MR, Le Rouzic V, Grinnell SG, Subrath JJ, Warner E, Kalra S, Hunkele A, Pagirsky J, Eans SO, Medina JM, Xu J, Pan YX, Borics A, Pasternak GW, McLaughlin JP, Majumdar S. Váradi A, et al. Among authors: grinnell sg. J Med Chem. 2016 Sep 22;59(18):8381-97. doi: 10.1021/acs.jmedchem.6b00748. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27556704 Free PMC article.
Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin.
Pickett JE, Nagakura K, Pasternak AR, Grinnell SG, Majumdar S, Lewis JS, Pasternak GW. Pickett JE, et al. Among authors: grinnell sg. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4347-50. doi: 10.1016/j.bmcl.2013.05.090. Epub 2013 Jun 6. Bioorg Med Chem Lett. 2013. PMID: 23796454 Free PMC article.
Mild, Pd-catalyzed stannylation of radioiodination targets.
Pickett JE, Váradi A, Palmer TC, Grinnell SG, Schrock JM, Pasternak GW, Karimov RR, Majumdar S. Pickett JE, et al. Among authors: grinnell sg. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1761-1764. doi: 10.1016/j.bmcl.2015.02.055. Epub 2015 Mar 2. Bioorg Med Chem Lett. 2015. PMID: 25777268 Free PMC article.
17 results