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Evidence that hyperglycemia after recovery from hypoglycemia worsens endothelial function and increases oxidative stress and inflammation in healthy control subjects and subjects with type 1 diabetes.
Ceriello A, Novials A, Ortega E, La Sala L, Pujadas G, Testa R, Bonfigli AR, Esposito K, Giugliano D. Ceriello A, et al. Among authors: pujadas g. Diabetes. 2012 Nov;61(11):2993-7. doi: 10.2337/db12-0224. Epub 2012 Aug 13. Diabetes. 2012. PMID: 22891214 Free PMC article. Clinical Trial.
Glucagon-like peptide 1 reduces endothelial dysfunction, inflammation, and oxidative stress induced by both hyperglycemia and hypoglycemia in type 1 diabetes.
Ceriello A, Novials A, Ortega E, Canivell S, La Sala L, Pujadas G, Esposito K, Giugliano D, Genovese S. Ceriello A, et al. Among authors: pujadas g. Diabetes Care. 2013 Aug;36(8):2346-50. doi: 10.2337/dc12-2469. Epub 2013 Apr 5. Diabetes Care. 2013. PMID: 23564922 Free PMC article. Clinical Trial.
Vitamin C further improves the protective effect of glucagon-like peptide-1 on acute hypoglycemia-induced oxidative stress, inflammation, and endothelial dysfunction in type 1 diabetes.
Ceriello A, Novials A, Ortega E, Canivell S, La Sala L, Pujadas G, Bucciarelli L, Rondinelli M, Genovese S. Ceriello A, et al. Among authors: pujadas g. Diabetes Care. 2013 Dec;36(12):4104-8. doi: 10.2337/dc13-0750. Epub 2013 Oct 15. Diabetes Care. 2013. PMID: 24130351 Free PMC article. Clinical Trial.
Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
Prattichizzo F, Giuliani A, De Nigris V, Pujadas G, Ceka A, La Sala L, Genovese S, Testa R, Procopio AD, Olivieri F, Ceriello A. Prattichizzo F, et al. Among authors: pujadas g. Diabetes Obes Metab. 2016 Sep;18(9):855-67. doi: 10.1111/dom.12688. Epub 2016 Jun 22. Diabetes Obes Metab. 2016. PMID: 27161301 Free PMC article. Review.
Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes.
Ceriello A, Novials A, Ortega E, Canivell S, Pujadas G, La Sala L, Bucciarelli L, Rondinelli M, Genovese S. Ceriello A, et al. Among authors: pujadas g. Cardiovasc Diabetol. 2013 Jun 27;12:97. doi: 10.1186/1475-2840-12-97. Cardiovasc Diabetol. 2013. PMID: 23806096 Free PMC article. Clinical Trial.
107 results