Ward RL - Search Results

1

The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype.

Kwok CT, Vogelaar IP, van Zelst-Stams WA, Mensenkamp AR, Ligtenberg MJ, Rapkins RW, Ward RL, Chun N, Ford JM, Ladabaum U, McKinnon WC, Greenblatt MS, Hitchins MP. Kwok CT, et al. Among authors: ward rl. Eur J Hum Genet. 2014 May;22(5):617-24. doi: 10.1038/ejhg.2013.200. Epub 2013 Oct 2. Eur J Hum Genet. 2014. PMID: 24084575 Free PMC article.

2

Germline epimutation of MLH1 in individuals with multiple cancers.

Suter CM, Martin DI, Ward RL. Suter CM, et al. Among authors: ward rl. Nat Genet. 2004 May;36(5):497-501. doi: 10.1038/ng1342. Epub 2004 Apr 4. Nat Genet. 2004. PMID: 15064764

3

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.

Hitchins M, Williams R, Cheong K, Halani N, Lin VA, Packham D, Ku S, Buckle A, Hawkins N, Burn J, Gallinger S, Goldblatt J, Kirk J, Tomlinson I, Scott R, Spigelman A, Suter C, Martin D, Suthers G, Ward R. Hitchins M, et al. Gastroenterology. 2005 Nov;129(5):1392-9. doi: 10.1053/j.gastro.2005.09.003. Gastroenterology. 2005. PMID: 16285940

4

Germline epimutations of APC are not associated with inherited colorectal polyposis.

Hitchins M, Suter C, Wong J, Cheong K, Hawkins N, Leggett B, Scott R, Spigelman A, Tomlinson I, Martin D, Ward R. Hitchins M, et al. Gut. 2006 Apr;55(4):586-7. doi: 10.1136/gut.2005.087486. Gut. 2006. PMID: 16531545 Free PMC article. No abstract available.

5

Inheritance of a cancer-associated MLH1 germ-line epimutation.

Hitchins MP, Wong JJ, Suthers G, Suter CM, Martin DI, Hawkins NJ, Ward RL. Hitchins MP, et al. Among authors: ward rl. N Engl J Med. 2007 Feb 15;356(7):697-705. doi: 10.1056/NEJMoa064522. N Engl J Med. 2007. PMID: 17301300 Free article.

6

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.

Hitchins MP, Lin VA, Buckle A, Cheong K, Halani N, Ku S, Kwok CT, Packham D, Suter CM, Meagher A, Stirzaker C, Clark S, Hawkins NJ, Ward RL. Hitchins MP, et al. Among authors: ward rl. Cancer Res. 2007 Oct 1;67(19):9107-16. doi: 10.1158/0008-5472.CAN-07-0869. Cancer Res. 2007. PMID: 17909015 Free article.

7

Erasure of MLH1 methylation in spermatozoa-implications for epigenetic inheritance.

Hitchins MP, Ward RL. Hitchins MP, et al. Among authors: ward rl. Nat Genet. 2007 Nov;39(11):1289. doi: 10.1038/ng1107-1289. Nat Genet. 2007. PMID: 17968340 No abstract available.

8

MLH1 germ-line epimutations: is there strong evidence of its inheritance?

Hitchins MP, Ward RL. Hitchins MP, et al. Among authors: ward rl. Gastroenterology. 2008 Jan;134(1):359-60. doi: 10.1053/j.gastro.2007.11.054. Gastroenterology. 2008. PMID: 18166368 No abstract available.

9

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.

Packham D, Ward RL, Ap Lin V, Hawkins NJ, Hitchins MP. Packham D, et al. Among authors: ward rl. Diagn Mol Pathol. 2009 Jun;18(2):62-71. doi: 10.1097/PDM.0b013e318182af52. Diagn Mol Pathol. 2009. PMID: 19430299

10

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.

Hawkins NJ, Lee JH, Wong JJ, Kwok CT, Ward RL, Hitchins MP. Hawkins NJ, et al. Among authors: ward rl. Mod Pathol. 2009 Dec;22(12):1588-99. doi: 10.1038/modpathol.2009.130. Epub 2009 Sep 4. Mod Pathol. 2009. PMID: 19734844 Free article.

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