Storz MP - Search Results

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Combining in silico and biophysical methods for the development of Pseudomonas aeruginosa quorum sensing inhibitors: an alternative approach for structure-based drug design.

Sahner JH, Brengel C, Storz MP, Groh M, Plaza A, Müller R, Hartmann RW. Sahner JH, et al. Among authors: storz mp. J Med Chem. 2013 Nov 14;56(21):8656-64. doi: 10.1021/jm401102e. Epub 2013 Oct 18. J Med Chem. 2013. PMID: 24083807

Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors.

Storz MP, Maurer CK, Zimmer C, Wagner N, Brengel C, de Jong JC, Lucas S, Müsken M, Häussler S, Steinbach A, Hartmann RW. Storz MP, et al. J Am Chem Soc. 2012 Oct 3;134(39):16143-6. doi: 10.1021/ja3072397. Epub 2012 Sep 24. J Am Chem Soc. 2012. PMID: 22992202

Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking.

Weidel E, de Jong JC, Brengel C, Storz MP, Braunshausen A, Negri M, Plaza A, Steinbach A, Müller R, Hartmann RW. Weidel E, et al. Among authors: storz mp. J Med Chem. 2013 Aug 8;56(15):6146-55. doi: 10.1021/jm4006302. Epub 2013 Jul 19. J Med Chem. 2013. PMID: 23834469

Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures.

Storz MP, Brengel C, Weidel E, Hoffmann M, Hollemeyer K, Steinbach A, Müller R, Empting M, Hartmann RW. Storz MP, et al. ACS Chem Biol. 2013 Dec 20;8(12):2794-801. doi: 10.1021/cb400530d. Epub 2013 Oct 25. ACS Chem Biol. 2013. PMID: 24099650

From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa.

Storz MP, Allegretta G, Kirsch B, Empting M, Hartmann RW. Storz MP, et al. Org Biomol Chem. 2014 Aug 28;12(32):6094-104. doi: 10.1039/c4ob00707g. Epub 2014 Jun 9. Org Biomol Chem. 2014. PMID: 24909330

Intramolecular hydroamination/cyclization of aminoalkenes catalyzed by Ln[N(SiMe(3))(2)](3) grafted onto periodic mesoporous silicas.

Le Roux E, Liang Y, Storz MP, Anwander R. Le Roux E, et al. Among authors: storz mp. J Am Chem Soc. 2010 Nov 24;132(46):16368-71. doi: 10.1021/ja107963u. Epub 2010 Oct 28. J Am Chem Soc. 2010. PMID: 21028823

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