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The landscape of somatic mutations in Down syndrome-related myeloid disorders.
Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Sanada M, Park MJ, Terui K, Suzuki H, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S. Yoshida K, et al. Among authors: izraeli s. Nat Genet. 2013 Nov;45(11):1293-9. doi: 10.1038/ng.2759. Epub 2013 Sep 22. Nat Genet. 2013. PMID: 24056718
The proto-oncogene ERG in megakaryoblastic leukemias.
Rainis L, Toki T, Pimanda JE, Rosenthal E, Machol K, Strehl S, Göttgens B, Ito E, Izraeli S. Rainis L, et al. Among authors: izraeli s. Cancer Res. 2005 Sep 1;65(17):7596-602. doi: 10.1158/0008-5472.CAN-05-0147. Cancer Res. 2005. PMID: 16140924
DYRK1A in Down syndrome: an oncogene or tumor suppressor?
Birger Y, Izraeli S. Birger Y, et al. Among authors: izraeli s. J Clin Invest. 2012 Mar;122(3):807-10. doi: 10.1172/JCI62372. Epub 2012 Feb 22. J Clin Invest. 2012. PMID: 22354166 Free PMC article.
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM. Lane AA, et al. Among authors: izraeli s. Nat Genet. 2014 Jun;46(6):618-23. doi: 10.1038/ng.2949. Epub 2014 Apr 20. Nat Genet. 2014. PMID: 24747640 Free PMC article.
Haematopoietic development and leukaemia in Down syndrome.
Roberts I, Izraeli S. Roberts I, et al. Among authors: izraeli s. Br J Haematol. 2014 Dec;167(5):587-99. doi: 10.1111/bjh.13096. Epub 2014 Aug 22. Br J Haematol. 2014. PMID: 25155832 Free article. Review.
MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome.
Shaham L, Vendramini E, Ge Y, Goren Y, Birger Y, Tijssen MR, McNulty M, Geron I, Schwartzman O, Goldberg L, Chou ST, Pitman H, Weiss MJ, Michaeli S, Sredni B, Göttgens B, Crispino JD, Taub JW, Izraeli S. Shaham L, et al. Among authors: izraeli s. Blood. 2015 Feb 19;125(8):1292-301. doi: 10.1182/blood-2014-06-581892. Epub 2014 Dec 22. Blood. 2015. PMID: 25533034 Free PMC article.
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
Brown AL, Arts P, Carmichael CL, Babic M, Dobbins J, Chong CE, Schreiber AW, Feng J, Phillips K, Wang PPS, Ha T, Homan CC, King-Smith SL, Rawlings L, Vakulin C, Dubowsky A, Burdett J, Moore S, McKavanagh G, Henry D, Wells A, Mercorella B, Nicola M, Suttle J, Wilkins E, Li XC, Michaud J, Brautigan P, Cannon P, Altree M, Jaensch L, Fine M, Butcher C, D'Andrea RJ, Lewis ID, Hiwase DK, Papaemmanuil E, Horwitz MS, Natsoulis G, Rienhoff HY, Patton N, Mapp S, Susman R, Morgan S, Cooney J, Currie M, Popat U, Bochtler T, Izraeli S, Bradstock K, Godley LA, Krämer A, Fröhling S, Wei AH, Forsyth C, Mar Fan H, Poplawski NK, Hahn CN, Scott HS. Brown AL, et al. Among authors: izraeli s. Blood Adv. 2020 Mar 24;4(6):1131-1144. doi: 10.1182/bloodadvances.2019000901. Blood Adv. 2020. PMID: 32208489 Free PMC article.
233 results