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Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium.
Davis DHJ, Skelly DT, Murray C, Hennessy E, Bowen J, Norton S, Brayne C, Rahkonen T, Sulkava R, Sanderson DJ, Rawlins JN, Bannerman DM, MacLullich AMJ, Cunningham C. Davis DHJ, et al. Among authors: skelly dt. Am J Geriatr Psychiatry. 2015 Apr;23(4):403-415. doi: 10.1016/j.jagp.2014.08.005. Epub 2014 Aug 15. Am J Geriatr Psychiatry. 2015. PMID: 25239680 Free PMC article.
Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age.
McGarry N, Murray CL, Garvey S, Wilkinson A, Tortorelli L, Ryan L, Hayden L, Healy D, Griffin EW, Hennessy E, Arumugam M, Skelly DT, Mitchell KJ, Cunningham C. McGarry N, et al. Among authors: skelly dt. Brain Behav Immun. 2021 Jul;95:413-428. doi: 10.1016/j.bbi.2021.04.016. Epub 2021 Apr 21. Brain Behav Immun. 2021. PMID: 33892139 Free PMC article.
Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age.
McGarry N, Murray CL, Garvey S, Wilkinson A, Tortorelli L, Ryan L, Hayden L, Healy D, Griffin EW, Hennessy E, Arumugam M, Skelly DT, Mitchell KJ, Cunningham C. McGarry N, et al. Among authors: skelly dt. bioRxiv [Preprint]. 2021 Jan 9:2021.01.09.426034. doi: 10.1101/2021.01.09.426034. bioRxiv. 2021. Update in: Brain Behav Immun. 2021 Jul;95:413-428. doi: 10.1016/j.bbi.2021.04.016. PMID: 33442686 Free PMC article. Updated. Preprint.
A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells.
Sampson O, Lim N, White J, Vieira V, Kløverpris H, Adland E, Conlon C, Skelly D, Jones L, Stafford L, Jamsen A, Barnes E, Dunachie S, Frater J, Klenerman P, Altfeld M, Goulder P. Sampson O, et al. J Immunol Methods. 2022 May;504:113263. doi: 10.1016/j.jim.2022.113263. Epub 2022 Mar 24. J Immunol Methods. 2022. PMID: 35341760 Free PMC article.
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