Rosen LS - Search Results

1

A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas.

Wagner AJ, Chugh R, Rosen LS, Morgan JA, George S, Gordon M, Dunbar J, Normant E, Grayzel D, Demetri GD. Wagner AJ, et al. Among authors: rosen ls. Clin Cancer Res. 2013 Nov 1;19(21):6020-9. doi: 10.1158/1078-0432.CCR-13-0953. Epub 2013 Sep 17. Clin Cancer Res. 2013. PMID: 24045182 Free PMC article. Clinical Trial.

2

Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies.

Rosen LS, Brown J, Laxa B, Boulos L, Reiswig L, Henner WD, Lum RT, Schow SR, Maack CA, Keck JG, Mascavage JC, Dombroski JA, Gomez RF, Brown GL. Rosen LS, et al. Clin Cancer Res. 2003 May;9(5):1628-38. Clin Cancer Res. 2003. PMID: 12738715 Clinical Trial.

3

Phase 1 study of TLK286 (Telcyta) administered weekly in advanced malignancies.

Rosen LS, Laxa B, Boulos L, Wiggins L, Keck JG, Jameson AJ, Parra R, Patel K, Brown GL. Rosen LS, et al. Clin Cancer Res. 2004 Jun 1;10(11):3689-98. doi: 10.1158/1078-0432.CCR-03-0687. Clin Cancer Res. 2004. PMID: 15173075 Clinical Trial.

4

Overview of anti-VEGF therapy and angiogenesis. Part 1: Angiogenesis inhibition in solid tumor malignancies.

Ellis LM, Rosen L, Gordon MS. Ellis LM, et al. Clin Adv Hematol Oncol. 2006 Jan;4(1):suppl 1-10; quz 11-2. Clin Adv Hematol Oncol. 2006. PMID: 16562372

5

Safety, pharmacokinetics, and efficacy of AMG 706, an oral multikinase inhibitor, in patients with advanced solid tumors.

Rosen LS, Kurzrock R, Mulay M, Van Vugt A, Purdom M, Ng C, Silverman J, Koutsoukos A, Sun YN, Bass MB, Xu RY, Polverino A, Wiezorek JS, Chang DD, Benjamin R, Herbst RS. Rosen LS, et al. J Clin Oncol. 2007 Jun 10;25(17):2369-76. doi: 10.1200/JCO.2006.07.8170. J Clin Oncol. 2007. PMID: 17557949 Clinical Trial.

6

Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors.

Tan AR, Rubin EH, Walton DC, Shuster DE, Wong YN, Fang F, Ashworth S, Rosen LS. Tan AR, et al. Among authors: rosen ls. Clin Cancer Res. 2009 Jun 15;15(12):4213-9. doi: 10.1158/1078-0432.CCR-09-0360. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509146 Clinical Trial.

7

Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors.

Herbst RS, Hong D, Chap L, Kurzrock R, Jackson E, Silverman JM, Rasmussen E, Sun YN, Zhong D, Hwang YC, Evelhoch JL, Oliner JD, Le N, Rosen LS. Herbst RS, et al. Among authors: rosen ls. J Clin Oncol. 2009 Jul 20;27(21):3557-65. doi: 10.1200/JCO.2008.19.6683. Epub 2009 Jun 22. J Clin Oncol. 2009. PMID: 19546406 Clinical Trial.

8

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis.

Houk BE, Bello CL, Poland B, Rosen LS, Demetri GD, Motzer RJ. Houk BE, et al. Among authors: rosen ls. Cancer Chemother Pharmacol. 2010 Jul;66(2):357-71. doi: 10.1007/s00280-009-1170-y. Epub 2009 Dec 5. Cancer Chemother Pharmacol. 2010. PMID: 19967539 Review.

9

Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors.

Johnson FM, Agrawal S, Burris H, Rosen L, Dhillon N, Hong D, Blackwood-Chirchir A, Luo FR, Sy O, Kaul S, Chiappori AA. Johnson FM, et al. Cancer. 2010 Mar 15;116(6):1582-91. doi: 10.1002/cncr.24927. Cancer. 2010. PMID: 20108303 Free article. Clinical Trial.

10

A phase I dose-escalation study of Tivantinib (ARQ 197) in adult patients with metastatic solid tumors.

Rosen LS, Senzer N, Mekhail T, Ganapathi R, Chai F, Savage RE, Waghorne C, Abbadessa G, Schwartz B, Dreicer R. Rosen LS, et al. Clin Cancer Res. 2011 Dec 15;17(24):7754-64. doi: 10.1158/1078-0432.CCR-11-1002. Epub 2011 Oct 5. Clin Cancer Res. 2011. PMID: 21976535 Clinical Trial.

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