Hoffman DC - Search Results

1

The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats.

Million M, Zhao JF, Luckey A, Czimmer J, Maynard GD, Kehne J, Hoffman DC, Taché Y. Million M, et al. Among authors: hoffman dc. PLoS One. 2013 Sep 6;8(9):e73749. doi: 10.1371/journal.pone.0073749. eCollection 2013. PLoS One. 2013. PMID: 24040053 Free PMC article.

2

Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.

Hodgetts KJ, Ge P, Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Kieltyka A, Horvath RF, Kehne JH, Krause JE, Maynard GD, Hoffman D, Lee Y, Fung L, Doller D. Hodgetts KJ, et al. J Med Chem. 2011 Jun 23;54(12):4187-206. doi: 10.1021/jm200365y. Epub 2011 May 27. J Med Chem. 2011. PMID: 21618986

3

2-Arylpyrimidines: novel CRF-1 receptor antagonists.

Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Krause JE, Hutchison A, Horvath RF, Ge P, Kehne J, Hoffman D, Chandrasekhar J, Doller D, Hodgetts KJ. Yoon T, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4486-90. doi: 10.1016/j.bmcl.2008.07.063. Epub 2008 Jul 18. Bioorg Med Chem Lett. 2008. PMID: 18672365

4

The design, synthesis and structure-activity relationships of 1-aryl-4-aminoalkylisoquinolines: a novel series of CRF-1 receptor antagonists.

Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Chandrasekhar J, Horvath RF, Ge P, Kershaw MT, Krause JE, Kehne J, Hoffman D, Doller D, Hodgetts KJ. Yoon T, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):891-6. doi: 10.1016/j.bmcl.2007.12.050. Epub 2008 Jan 3. Bioorg Med Chem Lett. 2008. PMID: 18180159

5

Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups.

Kehne JH, Coverdale S, McCloskey TC, Hoffman DC, Cassella JV. Kehne JH, et al. Among authors: hoffman dc. Neuropharmacology. 2000 Jun 8;39(8):1357-67. doi: 10.1016/s0028-3908(00)00043-5. Neuropharmacology. 2000. PMID: 10818252

6

The dopamine D(2) receptor partial agonist aplindore improves motor deficits in MPTP-treated common marmosets alone and combined with L-dopa.

Jackson MJ, Andree TH, Hansard M, Hoffman DC, Hurtt MR, Kehne JH, Pitler TA, Smith LA, Stack G, Jenner P. Jackson MJ, et al. Among authors: hoffman dc. J Neural Transm (Vienna). 2010 Jan;117(1):55-67. doi: 10.1007/s00702-009-0323-9. Epub 2009 Oct 7. J Neural Transm (Vienna). 2010. PMID: 19809864

7

ACSS2 gene variant associated with cleft lip and palate in two independent Hispanic populations.

Dodhia S, Celis K, Aylward A, Cai Y, Fontana ME, Trespalacios A, Hoffman DC, Alfonso HO, Eisig SB, Su GH, Chung WK, Haddad J Jr. Dodhia S, et al. Among authors: hoffman dc. Laryngoscope. 2017 Oct;127(10):E336-E339. doi: 10.1002/lary.26637. Epub 2017 May 23. Laryngoscope. 2017. PMID: 28543373 Free PMC article.

8

"The creation we behold": Thomas Paine's The Age of Reason and the tradition of physico-theology.

Hoffman DC. Hoffman DC. Proc Am Philos Soc. 2013 Sep;157(3):281-303. Proc Am Philos Soc. 2013. PMID: 25638828 No abstract available.

9

Percutaneous intradiscal aspiration of a lumbar vacuum disc herniation: a case report.

Pak KI, Hoffman DC, Herzog RJ, Lutz GE. Pak KI, et al. Among authors: hoffman dc. HSS J. 2011 Feb;7(1):89-93. doi: 10.1007/s11420-010-9168-x. Epub 2010 Aug 4. HSS J. 2011. PMID: 22294964 Free PMC article.

10

Concordance of retinal nerve fiber layer defects between fellow eyes of glaucoma patients measured by optical coherence tomography.

Bertuzzi F, Hoffman DC, De Fonseka AM, Souza C, Caprioli J. Bertuzzi F, et al. Among authors: hoffman dc. Am J Ophthalmol. 2009 Jul;148(1):148-54. doi: 10.1016/j.ajo.2009.02.009. Epub 2009 Apr 18. Am J Ophthalmol. 2009. PMID: 19375690 Clinical Trial.

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