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Epidermal deletion of HIF-2α stimulates wound closure.
Cowburn AS, Alexander LEC, Southwood M, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: southwood m. J Invest Dermatol. 2014 Mar;134(3):801-808. doi: 10.1038/jid.2013.395. Epub 2013 Sep 13. J Invest Dermatol. 2014. PMID: 24037341 Free PMC article.
HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: southwood m. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8801-6. doi: 10.1073/pnas.1602978113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432976 Free PMC article.
HIF isoforms in the skin differentially regulate systemic arterial pressure.
Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: southwood m. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17570-5. doi: 10.1073/pnas.1306942110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101470 Free PMC article.
Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.
Farahi N, Paige E, Balla J, Prudence E, Ferreira RC, Southwood M, Appleby SL, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Silverman EK, Cho MH, Danesh J, Paul DS, Freitag DF, Chilvers ER. Farahi N, et al. Among authors: southwood m. Hum Mol Genet. 2017 Apr 15;26(8):1584-1596. doi: 10.1093/hmg/ddx053. Hum Mol Genet. 2017. PMID: 28334838 Free PMC article.
Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
Li W, Long L, Yang X, Tong Z, Southwood M, King R, Caruso P, Upton PD, Yang P, Bocobo GA, Nikolic I, Higuera A, Salmon RM, Jiang H, Lodge KM, Hoenderdos K, Baron RM, Yu PB, Condliffe AM, Summers C, Nourshargh S, Chilvers ER, Morrell NW. Li W, et al. Among authors: southwood m. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1419-1430. doi: 10.1164/rccm.202005-1761OC. Am J Respir Crit Care Med. 2021. PMID: 33320799 Free PMC article.
Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.
Ormiston ML, Chang C, Long LL, Soon E, Jones D, Machado R, Treacy C, Toshner MR, Campbell K, Riding A, Southwood M, Pepke-Zaba J, Exley A, Trembath RC, Colucci F, Wills M, Trowsdale J, Morrell NW. Ormiston ML, et al. Among authors: southwood m. Circulation. 2012 Aug 28;126(9):1099-109. doi: 10.1161/CIRCULATIONAHA.112.110619. Epub 2012 Jul 25. Circulation. 2012. PMID: 22832786 Free article.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP. Yang P, et al. Among authors: southwood m. Circulation. 2017 Mar 21;135(12):1160-1173. doi: 10.1161/CIRCULATIONAHA.116.023218. Epub 2017 Jan 30. Circulation. 2017. PMID: 28137936 Free PMC article.
71 results