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Transgenic mouse model of the mild dominant form of osteogenesis imperfecta.
Bonadio J, Saunders TL, Tsai E, Goldstein SA, Morris-Wiman J, Brinkley L, Dolan DF, Altschuler RA, Hawkins JE Jr, Bateman JF, et al. Bonadio J, et al. Among authors: saunders tl. Proc Natl Acad Sci U S A. 1990 Sep;87(18):7145-9. doi: 10.1073/pnas.87.18.7145. Proc Natl Acad Sci U S A. 1990. PMID: 2402497 Free PMC article.
Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2.
Kommareddi P, Nair T, Kakaraparthi BN, Galano MM, Miller D, Laczkovich I, Thomas T, Lu L, Rule K, Kabara L, Kanicki A, Hughes ED, Jones JM, Hoenerhoff M, Fisher SG, Altschuler RA, Dolan D, Kohrman DC, Saunders TL, Carey TE. Kommareddi P, et al. Among authors: saunders tl. J Assoc Res Otolaryngol. 2015 Dec;16(6):695-712. doi: 10.1007/s10162-015-0547-3. J Assoc Res Otolaryngol. 2015. PMID: 26463873 Free PMC article.
Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits.
Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ 3rd, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, Scheuer T, Catterall WA, Isom LL. Chen C, et al. Among authors: saunders tl. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17072-7. doi: 10.1073/pnas.212638099. Epub 2002 Dec 12. Proc Natl Acad Sci U S A. 2002. PMID: 12481039 Free PMC article.
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration.
Ben-Yosef T, Belyantseva IA, Saunders TL, Hughes ED, Kawamoto K, Van Itallie CM, Beyer LA, Halsey K, Gardner DJ, Wilcox ER, Rasmussen J, Anderson JM, Dolan DF, Forge A, Raphael Y, Camper SA, Friedman TB. Ben-Yosef T, et al. Among authors: saunders tl. Hum Mol Genet. 2003 Aug 15;12(16):2049-61. doi: 10.1093/hmg/ddg210. Hum Mol Genet. 2003. PMID: 12913076
Inducible transgenic mouse models.
Saunders TL. Saunders TL. Methods Mol Biol. 2011;693:103-15. doi: 10.1007/978-1-60761-974-1_7. Methods Mol Biol. 2011. PMID: 21080277
Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.
Westrick RJ, Tomberg K, Siebert AE, Zhu G, Winn ME, Dobies SL, Manning SL, Brake MA, Cleuren AC, Hobbs LM, Mishack LM, Johnston AJ, Kotnik E, Siemieniak DR, Xu J, Li JZ, Saunders TL, Ginsburg D. Westrick RJ, et al. Among authors: saunders tl. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9659-9664. doi: 10.1073/pnas.1705762114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827327 Free PMC article.
Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.
Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D. Khoriaty R, et al. Among authors: saunders tl. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7748-E7757. doi: 10.1073/pnas.1805784115. Epub 2018 Jul 31. Proc Natl Acad Sci U S A. 2018. PMID: 30065114 Free PMC article.
169 results