Long MJ - Search Results

1

Temporally controlled targeting of 4-hydroxynonenal to specific proteins in living cells.

Fang X, Fu Y, Long MJ, Haegele JA, Ge EJ, Parvez S, Aye Y. Fang X, et al. Among authors: long mj. J Am Chem Soc. 2013 Oct 2;135(39):14496-9. doi: 10.1021/ja405400k. Epub 2013 Sep 18. J Am Chem Soc. 2013. PMID: 24015839 Free PMC article.

2

Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers.

Aye Y, Brignole EJ, Long MJ, Chittuluru J, Drennan CL, Asturias FJ, Stubbe J. Aye Y, et al. Among authors: long mj. Chem Biol. 2012 Jul 27;19(7):799-805. doi: 10.1016/j.chembiol.2012.05.015. Chem Biol. 2012. PMID: 22840768 Free PMC article.

3

Mechanistic studies of semicarbazone triapine targeting human ribonucleotide reductase in vitro and in mammalian cells: tyrosyl radical quenching not involving reactive oxygen species.

Aye Y, Long MJC, Stubbe J. Aye Y, et al. J Biol Chem. 2012 Oct 12;287(42):35768-35778. doi: 10.1074/jbc.M112.396911. Epub 2012 Aug 22. J Biol Chem. 2012. PMID: 22915594 Free PMC article.

4

Uncoupling of allosteric and oligomeric regulation in a functional hybrid enzyme constructed from Escherichia coli and human ribonucleotide reductase.

Fu Y, Long MJ, Rigney M, Parvez S, Blessing WA, Aye Y. Fu Y, et al. Among authors: long mj. Biochemistry. 2013 Oct 8;52(40):7050-9. doi: 10.1021/bi400781z. Epub 2013 Sep 23. Biochemistry. 2013. PMID: 24024562 Free PMC article.

5

Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies.

Aye Y, Li M, Long MJ, Weiss RS. Aye Y, et al. Among authors: long mj. Oncogene. 2015 Apr 16;34(16):2011-21. doi: 10.1038/onc.2014.155. Epub 2014 Jun 9. Oncogene. 2015. PMID: 24909171 Review.

6

Substoichiometric hydroxynonenylation of a single protein recapitulates whole-cell-stimulated antioxidant response.

Parvez S, Fu Y, Li J, Long MJ, Lin HY, Lee DK, Hu GS, Aye Y. Parvez S, et al. Among authors: long mj. J Am Chem Soc. 2015 Jan 14;137(1):10-3. doi: 10.1021/ja5084249. Epub 2014 Dec 31. J Am Chem Soc. 2015. PMID: 25544059 Free PMC article.

7

On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry.

Long MJ, Poganik JR, Aye Y. Long MJ, et al. J Am Chem Soc. 2016 Mar 23;138(11):3610-22. doi: 10.1021/jacs.5b12608. Epub 2016 Mar 7. J Am Chem Soc. 2016. PMID: 26907082 Free PMC article.

8

Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition.

Wisitpitthaya S, Zhao Y, Long MJ, Li M, Fletcher EA, Blessing WA, Weiss RS, Aye Y. Wisitpitthaya S, et al. Among authors: long mj. ACS Chem Biol. 2016 Jul 15;11(7):2021-32. doi: 10.1021/acschembio.6b00303. Epub 2016 May 20. ACS Chem Biol. 2016. PMID: 27159113 Free PMC article.

9

The Die Is Cast: Precision Electrophilic Modifications Contribute to Cellular Decision Making.

Long MJC, Aye Y. Long MJC, et al. Chem Res Toxicol. 2016 Oct 17;29(10):1575-1582. doi: 10.1021/acs.chemrestox.6b00261. Epub 2016 Oct 2. Chem Res Toxicol. 2016. PMID: 27617777 Free PMC article.

10

T-REX on-demand redox targeting in live cells.

Parvez S, Long MJ, Lin HY, Zhao Y, Haegele JA, Pham VN, Lee DK, Aye Y. Parvez S, et al. Among authors: long mj. Nat Protoc. 2016 Dec;11(12):2328-2356. doi: 10.1038/nprot.2016.114. Epub 2016 Oct 27. Nat Protoc. 2016. PMID: 27809314 Free PMC article.

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