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Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Abdul-Sater AA, et al. Among authors: allen ic. EMBO Rep. 2013 Oct;14(10):900-6. doi: 10.1038/embor.2013.132. Epub 2013 Sep 6. EMBO Rep. 2013. PMID: 24008845 Free PMC article.
Analysis of NLRP3 in the development of allergic airway disease in mice.
Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Allen IC, et al. J Immunol. 2012 Mar 15;188(6):2884-93. doi: 10.4049/jimmunol.1102488. Epub 2012 Feb 8. J Immunol. 2012. PMID: 22323538 Free PMC article.
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. Schneider M, et al. Among authors: allen ic. Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5. Nat Immunol. 2012. PMID: 22863753 Free PMC article.
144 results