Kadler KE - Search Results

1

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke.

Murray LS, Lu Y, Taggart A, Van Regemorter N, Vilain C, Abramowicz M, Kadler KE, Van Agtmael T. Murray LS, et al. Among authors: kadler ke. Hum Mol Genet. 2014 Jan 15;23(2):283-92. doi: 10.1093/hmg/ddt418. Epub 2013 Sep 2. Hum Mol Genet. 2014. PMID: 24001601 Free PMC article.

2

Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.

Leighton MP, Nundlall S, Starborg T, Meadows RS, Suleman F, Knowles L, Wagener R, Thornton DJ, Kadler KE, Boot-Handford RP, Briggs MD. Leighton MP, et al. Among authors: kadler ke. Hum Mol Genet. 2007 Jul 15;16(14):1728-41. doi: 10.1093/hmg/ddm121. Epub 2007 May 21. Hum Mol Genet. 2007. PMID: 17517694 Free PMC article.

3

Tendon development requires regulation of cell condensation and cell shape via cadherin-11-mediated cell-cell junctions.

Richardson SH, Starborg T, Lu Y, Humphries SM, Meadows RS, Kadler KE. Richardson SH, et al. Among authors: kadler ke. Mol Cell Biol. 2007 Sep;27(17):6218-28. doi: 10.1128/MCB.00261-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562872 Free PMC article.

4

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP.

Piróg-Garcia KA, Meadows RS, Knowles L, Heinegård D, Thornton DJ, Kadler KE, Boot-Handford RP, Briggs MD. Piróg-Garcia KA, et al. Among authors: kadler ke. Hum Mol Genet. 2007 Sep 1;16(17):2072-88. doi: 10.1093/hmg/ddm155. Epub 2007 Jun 22. Hum Mol Genet. 2007. PMID: 17588960 Free PMC article.

5

Active negative control of collagen fibrillogenesis in vivo. Intracellular cleavage of the type I procollagen propeptides in tendon fibroblasts without intracellular fibrils.

Humphries SM, Lu Y, Canty EG, Kadler KE. Humphries SM, et al. Among authors: kadler ke. J Biol Chem. 2008 May 2;283(18):12129-35. doi: 10.1074/jbc.M708198200. Epub 2008 Feb 19. J Biol Chem. 2008. PMID: 18285337 Free article.

6

Electron microscopy in cell-matrix research.

Starborg T, Lu Y, Meadows RS, Kadler KE, Holmes DF. Starborg T, et al. Among authors: kadler ke. Methods. 2008 May;45(1):53-64. doi: 10.1016/j.ymeth.2008.01.004. Methods. 2008. PMID: 18442705

7

Electron microscopy of collagen fibril structure in vitro and in vivo including three-dimensional reconstruction.

Starborg T, Lu Y, Kadler KE, Holmes DF. Starborg T, et al. Among authors: kadler ke. Methods Cell Biol. 2008;88:319-45. doi: 10.1016/S0091-679X(08)00417-2. Methods Cell Biol. 2008. PMID: 18617041 Review.

8

A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia.

Piróg KA, Jaka O, Katakura Y, Meadows RS, Kadler KE, Boot-Handford RP, Briggs MD. Piróg KA, et al. Among authors: kadler ke. Hum Mol Genet. 2010 Jan 1;19(1):52-64. doi: 10.1093/hmg/ddp466. Hum Mol Genet. 2010. PMID: 19808781 Free PMC article.

9

Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3.

Kapacee Z, Yeung CY, Lu Y, Crabtree D, Holmes DF, Kadler KE. Kapacee Z, et al. Among authors: kadler ke. Matrix Biol. 2010 Oct;29(8):668-77. doi: 10.1016/j.matbio.2010.08.005. Epub 2010 Aug 22. Matrix Biol. 2010. PMID: 20736064 Free PMC article.

10

Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation.

Taylor SH, Al-Youha S, Van Agtmael T, Lu Y, Wong J, McGrouther DA, Kadler KE. Taylor SH, et al. Among authors: kadler ke. PLoS One. 2011 Jan 26;6(1):e16337. doi: 10.1371/journal.pone.0016337. PLoS One. 2011. PMID: 21298098 Free PMC article.

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