Heynen-Genel S - Search Results

1

Identification of Inhibitors of triacylglyceride accumulation in muscle cells: comparing HTS results from 1536-well plate-based and high-content platforms.

Sugarman E, Koo A, Suyama E, Ruidiaz ME, Heynen-Genel S, Nguyen KH, Vasile S, Soundarapandian MM, Vega RB, Kelly DP, Smith LH, Malany S. Sugarman E, et al. J Biomol Screen. 2014 Jan;19(1):77-87. doi: 10.1177/1087057113501198. Epub 2013 Aug 29. J Biomol Screen. 2014. PMID: 23989452 Free PMC article.

2

A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs).

Yip KW, Cuddy M, Pinilla C, Giulanotti M, Heynen-Genel S, Matsuzawa S, Reed JC. Yip KW, et al. J Biomol Screen. 2011 Feb;16(2):251-8. doi: 10.1177/1087057110394181. Epub 2011 Jan 13. J Biomol Screen. 2011. PMID: 21233309 Free PMC article.

3

Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.

Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB. Peddibhotla S, et al. Among authors: heynen genel s. ACS Med Chem Lett. 2013 Jul 20;4(9):846-851. doi: 10.1021/ml400176n. ACS Med Chem Lett. 2013. PMID: 24611085 Free PMC article.

4

Optimization and application of median filter corrections to relieve diverse spatial patterns in microtiter plate data.

Bushway PJ, Azimi B, Heynen-Genel S. Bushway PJ, et al. J Biomol Screen. 2011 Oct;16(9):1068-80. doi: 10.1177/1087057111419028. Epub 2011 Sep 6. J Biomol Screen. 2011. PMID: 21900202 Free PMC article.

5

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, Heynen-Genel S, Mangravita-Novo A, Vicchiarelli M, Smith LH, Streicher JM, Caron MG, Barak LS, Bohn LM, Chung TD, Aubé J. Frankowski KJ, et al. ACS Chem Neurosci. 2012 Mar 21;3(3):221-236. doi: 10.1021/cn200128x. Epub 2012 Jan 20. ACS Chem Neurosci. 2012. PMID: 22737280 Free PMC article.

6

Functional genomic screen for modulators of ciliogenesis and cilium length.

Kim J, Lee JE, Heynen-Genel S, Suyama E, Ono K, Lee K, Ideker T, Aza-Blanc P, Gleeson JG. Kim J, et al. Nature. 2010 Apr 15;464(7291):1048-51. doi: 10.1038/nature08895. Nature. 2010. PMID: 20393563 Free PMC article.

7

Functional genomic and high-content screening for target discovery and deconvolution.

Heynen-Genel S, Pache L, Chanda SK, Rosen J. Heynen-Genel S, et al. Expert Opin Drug Discov. 2012 Oct;7(10):955-68. doi: 10.1517/17460441.2012.711311. Epub 2012 Aug 4. Expert Opin Drug Discov. 2012. PMID: 22860749 Free PMC article. Review.

8

Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen.

Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F. Kiselyuk A, et al. J Biomol Screen. 2010 Jul;15(6):663-70. doi: 10.1177/1087057110372257. Epub 2010 Jun 14. J Biomol Screen. 2010. PMID: 20547533 Free PMC article.

9

A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion.

Quintavalle M, Elia L, Price JH, Heynen-Genel S, Courtneidge SA. Quintavalle M, et al. Sci Signal. 2011 Jul 26;4(183):ra49. doi: 10.1126/scisignal.2002032. Sci Signal. 2011. PMID: 21791703 Free PMC article.

10

Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).

Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA. Milutinovic S, et al. Among authors: heynen genel s. PLoS One. 2016 Mar 31;11(3):e0152692. doi: 10.1371/journal.pone.0152692. eCollection 2016. PLoS One. 2016. PMID: 27031987 Free PMC article.

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