Lu Y - Search Results

1

Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury.

Oikawa M, Wu M, Lim S, Knight WE, Miller CL, Cai Y, Lu Y, Blaxall BC, Takeishi Y, Abe J, Yan C. Oikawa M, et al. Among authors: lu y. J Mol Cell Cardiol. 2013 Nov;64:11-9. doi: 10.1016/j.yjmcc.2013.08.003. Epub 2013 Aug 27. J Mol Cell Cardiol. 2013. PMID: 23988739 Free PMC article.

2

Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.

Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC. Satoh K, et al. Among authors: lu y. Arterioscler Thromb Vasc Biol. 2011 May;31(5):1116-23. doi: 10.1161/ATVBAHA.110.214601. Epub 2011 Feb 17. Arterioscler Thromb Vasc Biol. 2011. PMID: 21330604 Free PMC article.

3

p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.

Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. Le NT, et al. Among authors: lu y. Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19. Circ Res. 2012. PMID: 22267842 Free PMC article.

4

Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity.

Lu Z, Abe J, Taunton J, Lu Y, Shishido T, McClain C, Yan C, Xu SP, Spangenberg TM, Xu H. Lu Z, et al. Among authors: lu y. Circ Res. 2008 Aug 1;103(3):269-78. doi: 10.1161/CIRCRESAHA.107.166678. Epub 2008 Jul 3. Circ Res. 2008. PMID: 18599872 Free PMC article.

5

Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

Woo CH, Le NT, Shishido T, Chang E, Lee H, Heo KS, Mickelsen DM, Lu Y, McClain C, Spangenberg T, Yan C, Molina CA, Yang J, Patterson C, Abe J. Woo CH, et al. Among authors: lu y. FASEB J. 2010 Dec;24(12):4917-28. doi: 10.1096/fj.10-162636. Epub 2010 Aug 19. FASEB J. 2010. PMID: 20724525 Free PMC article.

6

Deletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunit.

Cai B, Wang N, Mao W, You T, Lu Y, Li X, Ye B, Li F, Xu H. Cai B, et al. Among authors: lu y. J Mol Cell Cardiol. 2014 Sep;74:297-306. doi: 10.1016/j.yjmcc.2014.06.006. Epub 2014 Jun 21. J Mol Cell Cardiol. 2014. PMID: 24956219 Free PMC article.

7

A small-molecule LF3 abrogates β-catenin/TCF4-mediated suppression of Na_V1.5 expression in HL-1 cardiomyocytes.

Zhao L, Sun L, Lu Y, Li F, Xu H. Zhao L, et al. Among authors: lu y. J Mol Cell Cardiol. 2019 Oct;135:90-96. doi: 10.1016/j.yjmcc.2019.08.007. Epub 2019 Aug 13. J Mol Cell Cardiol. 2019. PMID: 31419437 Free PMC article.

8

Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of Na_V1.5 expression.

Zhao L, You T, Lu Y, Lin S, Li F, Xu H. Zhao L, et al. Among authors: lu y. J Mol Cell Cardiol. 2021 Apr;153:95-103. doi: 10.1016/j.yjmcc.2020.12.012. Epub 2020 Dec 25. J Mol Cell Cardiol. 2021. PMID: 33370552 Free PMC article.

9

Enhancement of β-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing Na_V1.5 expression in mice.

Huo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu H. Huo R, et al. Among authors: lu y. Heart Rhythm. 2019 Nov;16(11):1720-1728. doi: 10.1016/j.hrthm.2019.05.015. Epub 2019 May 22. Heart Rhythm. 2019. PMID: 31125668 Free PMC article.

10

Activation of Wnt/β-catenin signaling by hydrogen peroxide transcriptionally inhibits NaV1.5 expression.

Wang N, Huo R, Cai B, Lu Y, Ye B, Li X, Li F, Xu H. Wang N, et al. Among authors: lu y. Free Radic Biol Med. 2016 Jul;96:34-44. doi: 10.1016/j.freeradbiomed.2016.04.003. Epub 2016 Apr 9. Free Radic Biol Med. 2016. PMID: 27068063 Free PMC article.

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