Gruzman A - Search Results

1

Multifunctional cyclic D,L-α-peptide architectures stimulate non-insulin dependent glucose uptake in skeletal muscle cells and protect them against oxidative stress.

Shapira R, Rudnick S, Daniel B, Viskind O, Aisha V, Richman M, Ayasolla KR, Perelman A, Chill JH, Gruzman A, Rahimipour S. Shapira R, et al. Among authors: gruzman a. J Med Chem. 2013 Sep 12;56(17):6709-18. doi: 10.1021/jm4005225. Epub 2013 Aug 28. J Med Chem. 2013. PMID: 23984871

2

Synthesis and characterization of new and potent alpha-lipoic acid derivatives.

Gruzman A, Hidmi A, Katzhendler J, Haj-Yehie A, Sasson S. Gruzman A, et al. Bioorg Med Chem. 2004 Mar 1;12(5):1183-90. doi: 10.1016/j.bmc.2003.11.025. Bioorg Med Chem. 2004. PMID: 14980629

3

Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase alpha.

Gruzman A, Shamni O, Ben Yakir M, Sandovski D, Elgart A, Alpert E, Cohen G, Hoffman A, Katzhendler Y, Cerasi E, Sasson S. Gruzman A, et al. J Med Chem. 2008 Dec 25;51(24):8096-108. doi: 10.1021/jm8008713. J Med Chem. 2008. PMID: 19049348

4

Antihyperglycaemic activity of 2,4:3,5-dibenzylidene-D-xylose-diethyl dithioacetal in diabetic mice.

Gruzman A, Elgart A, Viskind O, Billauer H, Dotan S, Cohen G, Mishani E, Hoffman A, Cerasi E, Sasson S. Gruzman A, et al. J Cell Mol Med. 2012 Mar;16(3):594-604. doi: 10.1111/j.1582-4934.2011.01340.x. J Cell Mol Med. 2012. PMID: 21564514 Free PMC article.

5

Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.

Meltzer-Mats E, Babai-Shani G, Pasternak L, Uritsky N, Getter T, Viskind O, Eckel J, Cerasi E, Senderowitz H, Sasson S, Gruzman A. Meltzer-Mats E, et al. Among authors: gruzman a. J Med Chem. 2013 Jul 11;56(13):5335-50. doi: 10.1021/jm4001488. Epub 2013 Jun 26. J Med Chem. 2013. PMID: 23750537

6

Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation.

Daniel B, Green O, Viskind O, Gruzman A. Daniel B, et al. Among authors: gruzman a. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):434-43. doi: 10.3109/21678421.2013.808226. Epub 2013 Jul 8. Amyotroph Lateral Scler Frontotemporal Degener. 2013. PMID: 23834207

7

Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via AMPK activation.

Pasternak L, Meltzer-Mats E, Babai-Shani G, Cohen G, Viskind O, Eckel J, Cerasi E, Sasson S, Gruzman A. Pasternak L, et al. Among authors: gruzman a. Chem Commun (Camb). 2014 Oct 4;50(76):11222-5. doi: 10.1039/c4cc03310h. Chem Commun (Camb). 2014. PMID: 25116279

8

Activators of AMPK: not just for type II diabetes.

Zaks I, Getter T, Gruzman A. Zaks I, et al. Among authors: gruzman a. Future Med Chem. 2014 Jul;6(11):1325-53. doi: 10.4155/fmc.14.74. Future Med Chem. 2014. PMID: 25163002 Review.

9

Antiproliferative Effect of Novel Aminoacridine-based Compounds.

Munder A, Moskovitz Y, Redko B, Levy AR, Ruthstein S, Gellerman G, Gruzman A. Munder A, et al. Among authors: gruzman a. Med Chem. 2015;11(4):373-82. doi: 10.2174/1573406411666141217110946. Med Chem. 2015. PMID: 25524547

10

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

Getter T, Zaks I, Barhum Y, Ben-Zur T, Böselt S, Gregoire S, Viskind O, Shani T, Gottlieb H, Green O, Shubely M, Senderowitz H, Israelson A, Kwon I, Petri S, Offen D, Gruzman A. Getter T, et al. Among authors: gruzman a. ChemMedChem. 2015 May;10(5):850-61. doi: 10.1002/cmdc.201500045. Epub 2015 Mar 13. ChemMedChem. 2015. PMID: 25772747

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