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Page 1
Highly efficient targeted mutagenesis in mice using TALENs.
Panda SK, Wefers B, Ortiz O, Floss T, Schmid B, Haass C, Wurst W, Kühn R. Panda SK, et al. Among authors: floss t. Genetics. 2013 Nov;195(3):703-13. doi: 10.1534/genetics.113.156570. Epub 2013 Aug 26. Genetics. 2013. PMID: 23979585 Free PMC article.
MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention.
Tischner C, Hofer A, Wulff V, Stepek J, Dumitru I, Becker L, Haack T, Kremer L, Datta AN, Sperl W, Floss T, Wurst W, Chrzanowska-Lightowlers Z, De Angelis MH, Klopstock T, Prokisch H, Wenz T. Tischner C, et al. Among authors: floss t. Hum Mol Genet. 2015 Apr 15;24(8):2247-66. doi: 10.1093/hmg/ddu743. Epub 2014 Dec 30. Hum Mol Genet. 2015. PMID: 25552653 Free PMC article.
Pleiotropic effects in Eya3 knockout mice.
Söker T, Dalke C, Puk O, Floss T, Becker L, Bolle I, Favor J, Hans W, Hölter SM, Horsch M, Kallnik M, Kling E, Moerth C, Schrewe A, Stigloher C, Topp S, Gailus-Durner V, Naton B, Beckers J, Fuchs H, Ivandic B, Klopstock T, Schulz H, Wolf E, Wurst W, Bally-Cuif L, de Angelis MH, Graw J. Söker T, et al. Among authors: floss t. BMC Dev Biol. 2008 Dec 22;8:118. doi: 10.1186/1471-213X-8-118. BMC Dev Biol. 2008. PMID: 19102749 Free PMC article.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Stribl C, Samara A, Trümbach D, Peis R, Neumann M, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Beckers J, Horsch M, Neff F, Kremmer E, Koob S, Reichert AS, Hans W, Rozman J, Klingenspor M, Aichler M, Walch AK, Becker L, Klopstock T, Glasl L, Hölter SM, Wurst W, Floss T. Stribl C, et al. Among authors: floss t. J Biol Chem. 2014 Apr 11;289(15):10769-10784. doi: 10.1074/jbc.M113.515940. Epub 2014 Feb 10. J Biol Chem. 2014. PMID: 24515116 Free PMC article.
Splinkerette PCR for more efficient characterization of gene trap events.
Horn C, Hansen J, Schnütgen F, Seisenberger C, Floss T, Irgang M, De-Zolt S, Wurst W, von Melchner H, Noppinger PR. Horn C, et al. Among authors: floss t. Nat Genet. 2007 Aug;39(8):933-4. doi: 10.1038/ng0807-933. Nat Genet. 2007. PMID: 17660805 No abstract available.
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.
Schebelle L, Wolf C, Stribl C, Javaheri T, Schnütgen F, Ettinger A, Ivics Z, Hansen J, Ruiz P, von Melchner H, Wurst W, Floss T. Schebelle L, et al. Among authors: floss t. Nucleic Acids Res. 2010 May;38(9):e106. doi: 10.1093/nar/gkq044. Epub 2010 Feb 5. Nucleic Acids Res. 2010. PMID: 20139417 Free PMC article.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.
Becker L, Kling E, Schiller E, Zeh R, Schrewe A, Hölter SM, Mossbrugger I, Calzada-Wack J, Strecker V, Wittig I, Dumitru I, Wenz T, Bender A, Aichler M, Janik D, Neff F, Walch A, Quintanilla-Fend L, Floss T, Bekeredjian R, Gailus-Durner V, Fuchs H, Wurst W, Meitinger T, Prokisch H, de Angelis MH, Klopstock T. Becker L, et al. Among authors: floss t. PLoS One. 2014 Dec 15;9(12):e114918. doi: 10.1371/journal.pone.0114918. eCollection 2014. PLoS One. 2014. PMID: 25506927 Free PMC article.
55 results