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Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ. van Loosdregt J, et al. Among authors: barbi j. Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018. Immunity. 2013. PMID: 23973222 Free PMC article.
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Among authors: barbi j. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.
Ubiquitous points of control over regulatory T cells.
Pan F, Barbi J. Pan F, et al. Among authors: barbi j. J Mol Med (Berl). 2014 Jun;92(6):555-69. doi: 10.1007/s00109-014-1156-z. Epub 2014 Apr 29. J Mol Med (Berl). 2014. PMID: 24777637 Free PMC article. Review.
The regulation of immune tolerance by FOXP3.
Lu L, Barbi J, Pan F. Lu L, et al. Among authors: barbi j. Nat Rev Immunol. 2017 Nov;17(11):703-717. doi: 10.1038/nri.2017.75. Epub 2017 Jul 31. Nat Rev Immunol. 2017. PMID: 28757603 Free PMC article. Review.
Metabolic control of the Treg/Th17 axis.
Barbi J, Pardoll D, Pan F. Barbi J, et al. Immunol Rev. 2013 Mar;252(1):52-77. doi: 10.1111/imr.12029. Immunol Rev. 2013. PMID: 23405895 Free PMC article. Review.
59 results