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Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases.
Gensollen T, Bourges C, Rihet P, Rostan A, Millet V, Noguchi T, Bourdon V, Sobol H, Dubuquoy L, Bertin B, Fumery M, Desreumaux P, Colombel JF, Chamaillard M, Hebuterne X, Hofman P, Naquet P, Galland F. Gensollen T, et al. Inflamm Bowel Dis. 2013 Oct;19(11):2315-25. doi: 10.1097/MIB.0b013e3182a32b03. Inflamm Bowel Dis. 2013. PMID: 23949622 Clinical Trial.
PPARalpha regulates the production of serum Vanin-1 by liver.
Rommelaere S, Millet V, Gensollen T, Bourges C, Eeckhoute J, Hennuyer N, Baugé E, Chasson L, Cacciatore I, Staels B, Pitari G, Galland F, Naquet P. Rommelaere S, et al. Among authors: gensollen t. FEBS Lett. 2013 Nov 15;587(22):3742-8. doi: 10.1016/j.febslet.2013.09.046. Epub 2013 Oct 15. FEBS Lett. 2013. PMID: 24140347 Free article.
Sox17 regulates liver lipid metabolism and adaptation to fasting.
Rommelaere S, Millet V, Vu Manh TP, Gensollen T, Andreoletti P, Cherkaoui-Malki M, Bourges C, Escalière B, Du X, Xia Y, Imbert J, Beutler B, Kanai Y, Malissen B, Malissen M, Tailleux A, Staels B, Galland F, Naquet P. Rommelaere S, et al. Among authors: gensollen t. PLoS One. 2014 Aug 20;9(8):e104925. doi: 10.1371/journal.pone.0104925. eCollection 2014. PLoS One. 2014. PMID: 25141153 Free PMC article.
Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis.
Millet V, Gensollen T, Maltese M, Serrero M, Lesavre N, Bourges C, Pitaval C, Cadra S, Chasson L, Vu Man TP, Masse M, Martinez-Garcia JJ, Tranchida F, Shintu L, Mostert K, Strauss E, Lepage P, Chamaillard M, Broggi A, Peyrin-Biroulet L, Grimaud JC, Naquet P, Galland F. Millet V, et al. Among authors: gensollen t. Gut. 2023 Jun;72(6):1115-1128. doi: 10.1136/gutjnl-2021-325792. Epub 2022 Sep 29. Gut. 2023. PMID: 36175116
Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity.
Giessner C, Millet V, Mostert KJ, Gensollen T, Vu Manh TP, Garibal M, Dieme B, Attaf-Bouabdallah N, Chasson L, Brouilly N, Laprie C, Lesluyes T, Blay JY, Shintu L, Martin JC, Strauss E, Galland F, Naquet P. Giessner C, et al. Among authors: gensollen t. Life Sci Alliance. 2018 Jul 23;1(4):e201800073. doi: 10.26508/lsa.201800073. eCollection 2018 Aug. Life Sci Alliance. 2018. PMID: 30456364 Free PMC article.
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