Griffin SA - Search Results

1

The effect of SV 293, a D2 dopamine receptor-selective antagonist, on D2 receptor-mediated GIRK channel activation and adenylyl cyclase inhibition.

Huang R, Griffin SA, Taylor M, Vangveravong S, Mach RH, Dillon GH, Luedtke RR. Huang R, et al. Among authors: griffin sa. Pharmacology. 2013;92(1-2):84-9. doi: 10.1159/000351971. Epub 2013 Aug 10. Pharmacology. 2013. PMID: 23942137

2

Evaluation of the D3 dopamine receptor selective antagonist PG01037 on L-dopa-dependent abnormal involuntary movements in rats.

Kumar R, Riddle L, Griffin SA, Grundt P, Newman AH, Luedtke RR. Kumar R, et al. Among authors: griffin sa. Neuropharmacology. 2009 May-Jun;56(6-7):944-55. doi: 10.1016/j.neuropharm.2009.01.020. Epub 2009 Feb 5. Neuropharmacology. 2009. PMID: 19371585 Free PMC article.

3

Evaluation of D2 and D3 dopamine receptor selective compounds on L-dopa-dependent abnormal involuntary movements in rats.

Kumar R, Riddle LR, Griffin SA, Chu W, Vangveravong S, Neisewander J, Mach RH, Luedtke RR. Kumar R, et al. Among authors: griffin sa. Neuropharmacology. 2009 May-Jun;56(6-7):956-69. doi: 10.1016/j.neuropharm.2009.01.019. Epub 2009 Feb 5. Neuropharmacology. 2009. PMID: 19371586 Free PMC article.

4

Dopamine D3 receptor selective ligands with varying intrinsic efficacies at adenylyl cyclase inhibition and mitogenic signaling pathways.

Taylor M, Grundt P, Griffin SA, Newman AH, Luedtke RR. Taylor M, et al. Among authors: griffin sa. Synapse. 2010 Mar;64(3):251-66. doi: 10.1002/syn.20725. Synapse. 2010. PMID: 19924694 Free PMC article.

5

Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds.

Luedtke RR, Mishra Y, Wang Q, Griffin SA, Bell-Horner C, Taylor M, Vangveravong S, Dillon GH, Huang RQ, Reichert DE, Mach RH. Luedtke RR, et al. Among authors: griffin sa. ACS Chem Neurosci. 2012 Dec 19;3(12):1050-62. doi: 10.1021/cn300142q. Epub 2012 Oct 12. ACS Chem Neurosci. 2012. PMID: 23259040 Free PMC article.

6

Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands.

Lee B, Taylor M, Griffin SA, McInnis T, Sumien N, Mach RH, Luedtke RR. Lee B, et al. Among authors: griffin sa. Molecules. 2021 May 26;26(11):3182. doi: 10.3390/molecules26113182. Molecules. 2021. PMID: 34073405 Free PMC article.

7

Typical antipsychotics exhibit inverse agonist activity at rat dopamine D1-like receptors expressed in Sf9 cells.

Martin MW, Scott AW, Johnston DE Jr, Griffin S, Luedtke RR. Martin MW, et al. Eur J Pharmacol. 2001 May 25;420(2-3):73-82. doi: 10.1016/s0014-2999(01)00982-7. Eur J Pharmacol. 2001. PMID: 11408027

8

Highly Selective Dopamine D₃ Receptor Antagonists with Arylated Diazaspiro Alkane Cores.

Reilly SW, Griffin S, Taylor M, Sahlholm K, Weng CC, Xu K, Jacome DA, Luedtke RR, Mach RH. Reilly SW, et al. J Med Chem. 2017 Dec 14;60(23):9905-9910. doi: 10.1021/acs.jmedchem.7b01248. Epub 2017 Nov 21. J Med Chem. 2017. PMID: 29125762 Free PMC article.

9

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D₃ Receptor (D₃R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs).

Reilly SW, Riad AA, Hsieh CJ, Sahlholm K, Jacome DA, Griffin S, Taylor M, Weng CC, Xu K, Kirschner N, Luedtke RR, Parry C, Malhotra S, Karanicolas J, Mach RH. Reilly SW, et al. J Med Chem. 2019 May 23;62(10):5132-5147. doi: 10.1021/acs.jmedchem.9b00412. Epub 2019 May 6. J Med Chem. 2019. PMID: 31021617

10

The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors.

Silvano E, Millan MJ, Mannoury la Cour C, Han Y, Duan L, Griffin SA, Luedtke RR, Aloisi G, Rossi M, Zazzeroni F, Javitch JA, Maggio R. Silvano E, et al. Among authors: griffin sa. Mol Pharmacol. 2010 Nov;78(5):925-34. doi: 10.1124/mol.110.065755. Epub 2010 Aug 11. Mol Pharmacol. 2010. PMID: 20702763 Free PMC article.

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