Monahan PE - Search Results

1

Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in Hemophilia B mice.

Suwanmanee T, Hu G, Gui T, Bartholomae CC, Kutschera I, von Kalle C, Schmidt M, Monahan PE, Kafri T. Suwanmanee T, et al. Among authors: monahan pe. Mol Ther. 2014 Mar;22(3):567-574. doi: 10.1038/mt.2013.188. Epub 2013 Aug 14. Mol Ther. 2014. PMID: 23941813 Free PMC article.

2

Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia.

Monahan PE, Samulski RJ, Tazelaar J, Xiao X, Nichols TC, Bellinger DA, Read MS, Walsh CE. Monahan PE, et al. Gene Ther. 1998 Jan;5(1):40-9. doi: 10.1038/sj.gt.3300548. Gene Ther. 1998. PMID: 9536263

3

Persistent expression of canine factor IX in hemophilia B canines.

Chao H, Samulski R, Bellinger D, Monahan P, Nichols T, Walsh C. Chao H, et al. Gene Ther. 1999 Oct;6(10):1695-704. doi: 10.1038/sj.gt.3301024. Gene Ther. 1999. PMID: 10516718

4

AAV vectors: is clinical success on the horizon?

Monahan PE, Samulski RJ. Monahan PE, et al. Gene Ther. 2000 Jan;7(1):24-30. doi: 10.1038/sj.gt.3301109. Gene Ther. 2000. PMID: 10680012 Review.

5

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis.

McCarty DM, Monahan PE, Samulski RJ. McCarty DM, et al. Among authors: monahan pe. Gene Ther. 2001 Aug;8(16):1248-54. doi: 10.1038/sj.gt.3301514. Gene Ther. 2001. PMID: 11509958

6

Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors.

Chao H, Monahan PE, Liu Y, Samulski RJ, Walsh CE. Chao H, et al. Among authors: monahan pe. Mol Ther. 2001 Sep;4(3):217-22. doi: 10.1006/mthe.2001.0449. Mol Ther. 2001. PMID: 11545612 Free article.

7

Hemophilia gene therapy: update.

Monahan PE, White GC 2nd. Monahan PE, et al. Curr Opin Hematol. 2002 Sep;9(5):430-6. doi: 10.1097/00062752-200209000-00007. Curr Opin Hematol. 2002. PMID: 12172462 Review.

8

Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo.

McCarty DM, Fu H, Monahan PE, Toulson CE, Naik P, Samulski RJ. McCarty DM, et al. Among authors: monahan pe. Gene Ther. 2003 Dec;10(26):2112-8. doi: 10.1038/sj.gt.3302134. Gene Ther. 2003. PMID: 14625565

9

Creation of a mouse expressing defective human factor IX.

Jin DY, Zhang TP, Gui T, Stafford DW, Monahan PE. Jin DY, et al. Among authors: monahan pe. Blood. 2004 Sep 15;104(6):1733-9. doi: 10.1182/blood-2004-01-0138. Epub 2004 Jun 3. Blood. 2004. PMID: 15178576 Free article.

10

Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice.

Zhang TP, Jin DY, Wardrop RM 3rd, Gui T, Maile R, Frelinger JA, Stafford DW, Monahan PE. Zhang TP, et al. Among authors: monahan pe. Gene Ther. 2007 Mar;14(5):429-40. doi: 10.1038/sj.gt.3302881. Epub 2006 Oct 26. Gene Ther. 2007. PMID: 17066096

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