Young M - Search Results

1

Cited1 deficiency suppresses intestinal tumorigenesis.

Méniel V, Song F, Phesse T, Young M, Poetz O, Parry L, Jenkins JR, Williams GT, Dunwoodie SL, Watson A, Clarke AR. Méniel V, et al. Among authors: young m. PLoS Genet. 2013;9(8):e1003638. doi: 10.1371/journal.pgen.1003638. Epub 2013 Aug 1. PLoS Genet. 2013. PMID: 23935526 Free PMC article.

2

Subtle Deregulation of the Wnt-Signaling Pathway Through Loss of Apc2 Reduces the Fitness of Intestinal Stem Cells.

Young MA, Daly CS, Taylor E, James R, Clarke AR, Reed KR. Young MA, et al. Stem Cells. 2018 Jan;36(1):114-122. doi: 10.1002/stem.2712. Epub 2017 Oct 13. Stem Cells. 2018. PMID: 29027285 Free PMC article.

3

Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice.

Reed KR, Tunster SJ, Young M, Carrico A, John RM, Clarke AR. Reed KR, et al. Among authors: young m. Gut. 2012 Oct;61(10):1435-8. doi: 10.1136/gutjnl-2011-300842. Epub 2011 Dec 3. Gut. 2012. PMID: 22138533

4

Evidence for a crucial role of paneth cells in mediating the intestinal response to injury.

Parry L, Young M, El Marjou F, Clarke AR. Parry L, et al. Among authors: young m. Stem Cells. 2013 Apr;31(4):776-85. doi: 10.1002/stem.1326. Stem Cells. 2013. PMID: 23335179 Free PMC article.

5

Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine.

Holik AZ, Young M, Krzystyniak J, Williams GT, Metzger D, Shorning BY, Clarke AR. Holik AZ, et al. Among authors: young m. PLoS Genet. 2014 Jul 10;10(7):e1004453. doi: 10.1371/journal.pgen.1004453. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25010414 Free PMC article.

6

Apc and p53 interaction in DNA damage and genomic instability in hepatocytes.

Méniel V, Megges M, Young MA, Cole A, Sansom OJ, Clarke AR. Méniel V, et al. Among authors: young ma. Oncogene. 2015 Jul 30;34(31):4118-29. doi: 10.1038/onc.2014.342. Epub 2014 Oct 27. Oncogene. 2015. PMID: 25347740 Free PMC article.

7

Epigenetic Regulation of Dlg1, via Kaiso, Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis.

Young MA, May S, Damo A, Yoon YS, Hur MW, Swat W, Parry L. Young MA, et al. Mol Cancer Res. 2019 Mar;17(3):686-696. doi: 10.1158/1541-7786.MCR-18-0280. Epub 2018 Dec 14. Mol Cancer Res. 2019. PMID: 30552232 Free article.

8

Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.

Holik AZ, Krzystyniak J, Young M, Richardson K, Jardé T, Chambon P, Shorning BY, Clarke AR. Holik AZ, et al. Among authors: young m. Stem Cells. 2013 Nov;31(11):2457-66. doi: 10.1002/stem.1498. Stem Cells. 2013. PMID: 23922304

9

Protocols for Analyzing the Role of Paneth Cells in Regenerating the Murine Intestine using Conditional Cre-lox Mouse Models.

Parry L, Young M, El Marjou F, Clarke AR. Parry L, et al. Among authors: young m. J Vis Exp. 2015 Nov 21;(105):53429. doi: 10.3791/53429. J Vis Exp. 2015. PMID: 26649885 Free PMC article.

10

What are the best routes to effectively model human colorectal cancer?

Young M, Ordonez L, Clarke AR. Young M, et al. Mol Oncol. 2013 Apr;7(2):178-89. doi: 10.1016/j.molonc.2013.02.006. Epub 2013 Feb 20. Mol Oncol. 2013. PMID: 23465602 Free PMC article. Review.

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