Markley LD - Search Results

1

Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis.

Moraski GC, Markley LD, Cramer J, Hipskind PA, Boshoff H, Bailey M, Alling T, Ollinger J, Parish T, Miller MJ. Moraski GC, et al. Among authors: markley ld. ACS Med Chem Lett. 2013 Jul 11;4(7):675-679. doi: 10.1021/ml400088y. ACS Med Chem Lett. 2013. PMID: 23930153 Free PMC article.

2

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity.

Moraski GC, Markley LD, Hipskind PA, Boshoff H, Cho S, Franzblau SG, Miller MJ. Moraski GC, et al. Among authors: markley ld. ACS Med Chem Lett. 2011 Jun 9;2(6):466-470. doi: 10.1021/ml200036r. ACS Med Chem Lett. 2011. PMID: 21691438 Free PMC article.

3

Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds.

Moraski GC, Markley LD, Chang M, Cho S, Franzblau SG, Hwang CH, Boshoff H, Miller MJ. Moraski GC, et al. Among authors: markley ld. Bioorg Med Chem. 2012 Apr 1;20(7):2214-20. doi: 10.1016/j.bmc.2012.02.025. Epub 2012 Feb 16. Bioorg Med Chem. 2012. PMID: 22391032 Free PMC article.

4

Scaffold-switching: an exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates.

Moraski GC, Oliver AG, Markley LD, Cho S, Franzblau SG, Miller MJ. Moraski GC, et al. Among authors: markley ld. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3493-8. doi: 10.1016/j.bmcl.2014.05.062. Epub 2014 May 28. Bioorg Med Chem Lett. 2014. PMID: 24909079 Free PMC article.

5

Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds.

Liu R, Markley L, Miller PA, Franzblau S, Shetye G, Ma R, Savková K, Mikušová K, Lee BS, Pethe K, Moraski GC, Miller MJ. Liu R, et al. RSC Med Chem. 2021 Jan 4;12(1):62-72. doi: 10.1039/d0md00390e. eCollection 2021 Jan 1. RSC Med Chem. 2021. PMID: 34046598 Free PMC article.

6

Antipicornavirus activity of substituted phenoxybenzenes and phenoxypyridines.

Markley LD, Tong YC, Dulworth JK, Steward DL, Goralski CT, Johnston H, Wood SG, Vinogradoff AP, Bargar TM. Markley LD, et al. J Med Chem. 1986 Mar;29(3):427-33. doi: 10.1021/jm00153a020. J Med Chem. 1986. PMID: 3005578

7

Synthesis and anticoccidial activity of 3-fluoro-5-chloro- and -bromo-2,6-dimethyl-4-pyridinol.

Markley LD, Eckman MK. Markley LD, et al. J Med Chem. 1973 Mar;16(3):297-8. doi: 10.1021/jm00261a033. J Med Chem. 1973. PMID: 4733114 No abstract available.

8

Solid phase synthesis and antibacterial activity of N-terminal sequences of melittin.

Dorman LC, Markley LD. Dorman LC, et al. Among authors: markley ld. J Med Chem. 1971 Jan;14(1):5-9. doi: 10.1021/jm00283a003. J Med Chem. 1971. PMID: 5539751 No abstract available.

9

Characterization of the Anopheles gambiae octopamine receptor and discovery of potential agonists and antagonists using a combined computational-experimental approach.

Kastner KW, Shoue DA, Estiu GL, Wolford J, Fuerst MF, Markley LD, Izaguirre JA, McDowell MA. Kastner KW, et al. Among authors: markley ld. Malar J. 2014 Nov 18;13:434. doi: 10.1186/1475-2875-13-434. Malar J. 2014. PMID: 25407998 Free PMC article.

10

A comparative study of terminating agents for use in solid-phase peptide synthesis.

Markley LD, Dorman LC. Markley LD, et al. Tetrahedron Lett. 1970 May;(21):1787-90. doi: 10.1016/s0040-4039(01)98083-9. Tetrahedron Lett. 1970. PMID: 5433531 No abstract available.

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