Tang WJ - Search Results

1

Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.

McCord LA, Liang WG, Dowdell E, Kalas V, Hoey RJ, Koide A, Koide S, Tang WJ. McCord LA, et al. Among authors: tang wj. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13827-32. doi: 10.1073/pnas.1304575110. Epub 2013 Aug 6. Proc Natl Acad Sci U S A. 2013. PMID: 23922390 Free PMC article.

2

Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.

Shen Y, Zhukovskaya NL, Zimmer MI, Soelaiman S, Bergson P, Wang CR, Gibbs CS, Tang WJ. Shen Y, et al. Among authors: tang wj. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3242-7. doi: 10.1073/pnas.0306552101. Epub 2004 Feb 20. Proc Natl Acad Sci U S A. 2004. PMID: 14978283 Free PMC article.

3

The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition.

Li P, Kuo WL, Yousef M, Rosner MR, Tang WJ. Li P, et al. Among authors: tang wj. Biochem Biophys Res Commun. 2006 May 19;343(4):1032-7. doi: 10.1016/j.bbrc.2006.03.083. Epub 2006 Mar 22. Biochem Biophys Res Commun. 2006. PMID: 16574064

4

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.

Shen Y, Joachimiak A, Rosner MR, Tang WJ. Shen Y, et al. Among authors: tang wj. Nature. 2006 Oct 19;443(7113):870-4. doi: 10.1038/nature05143. Epub 2006 Oct 11. Nature. 2006. PMID: 17051221 Free PMC article.

5

Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.

Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Im H, et al. Among authors: tang wj. J Biol Chem. 2007 Aug 31;282(35):25453-63. doi: 10.1074/jbc.M701590200. Epub 2007 Jul 5. J Biol Chem. 2007. PMID: 17613531 Free article.

6

Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme.

Malito E, Ralat LA, Manolopoulou M, Tsay JL, Wadlington NL, Tang WJ. Malito E, et al. Among authors: tang wj. Biochemistry. 2008 Dec 2;47(48):12822-34. doi: 10.1021/bi801192h. Biochemistry. 2008. PMID: 18986166 Free PMC article.

7

Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme.

Manolopoulou M, Guo Q, Malito E, Schilling AB, Tang WJ. Manolopoulou M, et al. Among authors: tang wj. J Biol Chem. 2009 May 22;284(21):14177-88. doi: 10.1074/jbc.M900068200. Epub 2009 Mar 25. J Biol Chem. 2009. PMID: 19321446 Free PMC article.

8

Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme.

Chou YH, Kuo WL, Rosner MR, Tang WJ, Goldman RD. Chou YH, et al. Among authors: tang wj. FASEB J. 2009 Nov;23(11):3734-42. doi: 10.1096/fj.09-137455. Epub 2009 Jul 7. FASEB J. 2009. PMID: 19584300 Free PMC article.

9

Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation.

Ralat LA, Ren M, Schilling AB, Tang WJ. Ralat LA, et al. Among authors: tang wj. J Biol Chem. 2009 Dec 4;284(49):34005-18. doi: 10.1074/jbc.M109.030627. Epub 2009 Oct 6. J Biol Chem. 2009. PMID: 19808678 Free PMC article.

10

Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.

Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Guo Q, et al. Among authors: tang wj. J Mol Biol. 2010 Jan 15;395(2):430-43. doi: 10.1016/j.jmb.2009.10.072. Epub 2009 Nov 5. J Mol Biol. 2010. PMID: 19896952 Free PMC article.

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