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HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N. Sivakumaran V, et al. Among authors: ziolo mt. Antioxid Redox Signal. 2013 Oct 10;19(11):1185-97. doi: 10.1089/ars.2012.5057. Antioxid Redox Signal. 2013. PMID: 23919584 Free PMC article.
The lack of Troponin I Ser-23/24 phosphorylation is detrimental to in vivo cardiac function and exacerbates cardiac disease.
Salhi HE, Shettigar V, Salyer L, Sturgill S, Brundage EA, Robinett J, Xu Z, Abay E, Lowe J, Janssen PML, Rafael-Fortney JA, Weisleder N, Ziolo MT, Biesiadecki BJ. Salhi HE, et al. Among authors: ziolo mt. J Mol Cell Cardiol. 2023 Mar;176:84-96. doi: 10.1016/j.yjmcc.2023.01.010. Epub 2023 Jan 29. J Mol Cell Cardiol. 2023. PMID: 36724829 Free PMC article.
Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function.
Salyer LG, Salhi HE, Brundage EA, Shettigar V, Sturgill SL, Zanella H, Templeton B, Abay E, Emmer KM, Lowe J, Rafael-Fortney JA, Parinandi N, Foster DB, McKinsey TA, Woulfe KC, Ziolo MT, Biesiadecki BJ. Salyer LG, et al. Among authors: ziolo mt. Circ Res. 2024 Jan 5;134(1):33-45. doi: 10.1161/CIRCRESAHA.123.323132. Epub 2023 Dec 14. Circ Res. 2024. PMID: 38095088 Free PMC article.
Biphasic effect of SIN-1 is reliant upon cardiomyocyte contractile state.
Kohr MJ, Wang H, Wheeler DG, Velayutham M, Zweier JL, Ziolo MT. Kohr MJ, et al. Among authors: ziolo mt. Free Radic Biol Med. 2008 Jul 1;45(1):73-80. doi: 10.1016/j.freeradbiomed.2008.03.019. Epub 2008 Apr 4. Free Radic Biol Med. 2008. PMID: 18433725 Free PMC article.
Modulation of myocardial contraction by peroxynitrite.
Kohr MJ, Roof SR, Zweier JL, Ziolo MT. Kohr MJ, et al. Among authors: ziolo mt. Front Physiol. 2012 Dec 12;3:468. doi: 10.3389/fphys.2012.00468. eCollection 2012. Front Physiol. 2012. PMID: 23248603 Free PMC article.
83 results