Wilkes MC - Search Results

1

Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases.

Andrianifahanana M, Wilkes MC, Gupta SK, Rahimi RA, Repellin CE, Edens M, Wittenberger J, Yin X, Maidl E, Becker J, Leof EB. Andrianifahanana M, et al. Among authors: wilkes mc. FASEB J. 2013 Nov;27(11):4444-54. doi: 10.1096/fj.12-224907. Epub 2013 Aug 2. FASEB J. 2013. PMID: 23913859 Free PMC article.

2

ERBB receptor activation is required for profibrotic responses to transforming growth factor beta.

Andrianifahanana M, Wilkes MC, Repellin CE, Edens M, Kottom TJ, Rahimi RA, Leof EB. Andrianifahanana M, et al. Among authors: wilkes mc. Cancer Res. 2010 Oct 1;70(19):7421-30. doi: 10.1158/0008-5472.CAN-10-0232. Epub 2010 Sep 14. Cancer Res. 2010. PMID: 20841477 Free PMC article.

3

Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells.

Murphy SJ, Doré JJ, Edens M, Coffey RJ, Barnard JA, Mitchell H, Wilkes M, Leof EB. Murphy SJ, et al. Mol Biol Cell. 2004 Jun;15(6):2853-62. doi: 10.1091/mbc.e04-02-0097. Epub 2004 Apr 9. Mol Biol Cell. 2004. PMID: 15075369 Free PMC article.

4

Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3.

Wilkes MC, Murphy SJ, Garamszegi N, Leof EB. Wilkes MC, et al. Mol Cell Biol. 2003 Dec;23(23):8878-89. doi: 10.1128/MCB.23.23.8878-8889.2003. Mol Cell Biol. 2003. PMID: 14612425 Free PMC article.

5

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.

Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB. Daniels CE, et al. Among authors: wilkes mc. J Clin Invest. 2004 Nov;114(9):1308-16. doi: 10.1172/JCI19603. J Clin Invest. 2004. PMID: 15520863 Free PMC article.

6

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo.

Wang S, Wilkes MC, Leof EB, Hirschberg R. Wang S, et al. Among authors: wilkes mc. FASEB J. 2005 Jan;19(1):1-11. doi: 10.1096/fj.04-2370com. FASEB J. 2005. PMID: 15629889

7

Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures.

Wilkes MC, Leof EB. Wilkes MC, et al. J Biol Chem. 2006 Sep 22;281(38):27846-54. doi: 10.1074/jbc.M603721200. Epub 2006 Jul 24. J Biol Chem. 2006. PMID: 16867995 Free article.

8

Transforming growth factor beta signaling via Ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses.

Suzuki K, Wilkes MC, Garamszegi N, Edens M, Leof EB. Suzuki K, et al. Among authors: wilkes mc. Cancer Res. 2007 Apr 15;67(8):3673-82. doi: 10.1158/0008-5472.CAN-06-3211. Cancer Res. 2007. PMID: 17440079

9

Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.

Rahimi RA, Andrianifahanana M, Wilkes MC, Edens M, Kottom TJ, Blenis J, Leof EB. Rahimi RA, et al. Among authors: wilkes mc. Cancer Res. 2009 Jan 1;69(1):84-93. doi: 10.1158/0008-5472.CAN-08-2146. Cancer Res. 2009. PMID: 19117990 Free PMC article.

10

Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.

Wilkes MC, Repellin CE, Hong M, Bracamonte M, Penheiter SG, Borg JP, Leof EB. Wilkes MC, et al. Dev Cell. 2009 Mar;16(3):433-44. doi: 10.1016/j.devcel.2009.01.009. Dev Cell. 2009. PMID: 19289088 Free PMC article.

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