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Computational approaches to identify functional genetic variants in cancer genomes.
Gonzalez-Perez A, Mustonen V, Reva B, Ritchie GR, Creixell P, Karchin R, Vazquez M, Fink JL, Kassahn KS, Pearson JV, Bader GD, Boutros PC, Muthuswamy L, Ouellette BF, Reimand J, Linding R, Shibata T, Valencia A, Butler A, Dronov S, Flicek P, Shannon NB, Carter H, Ding L, Sander C, Stuart JM, Stein LD, Lopez-Bigas N; International Cancer Genome Consortium Mutation Pathways and Consequences Subgroup of the Bioinformatics Analyses Working Group. Gonzalez-Perez A, et al. Among authors: linding r. Nat Methods. 2013 Aug;10(8):723-9. doi: 10.1038/nmeth.2562. Nat Methods. 2013. PMID: 23900255 Free PMC article.
Cells, shared memory and breaking the PTM code.
Creixell P, Linding R. Creixell P, et al. Among authors: linding r. Mol Syst Biol. 2012;8:598. doi: 10.1038/msb.2012.33. Mol Syst Biol. 2012. PMID: 22866336 Free PMC article. No abstract available.
Pathway and network analysis of cancer genomes.
Creixell P, Reimand J, Haider S, Wu G, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, Boutros PC, Stuart JM, Linding R, Lopez-Bigas N, Stein LD; Mutation Consequences and Pathway Analysis Working Group of the International Cancer Genome Consortium. Creixell P, et al. Among authors: linding r. Nat Methods. 2015 Jul;12(7):615-621. doi: 10.1038/nmeth.3440. Nat Methods. 2015. PMID: 26125594 Free PMC article.
Unmasking determinants of specificity in the human kinome.
Creixell P, Palmeri A, Miller CJ, Lou HJ, Santini CC, Nielsen M, Turk BE, Linding R. Creixell P, et al. Among authors: linding r. Cell. 2015 Sep 24;163(1):187-201. doi: 10.1016/j.cell.2015.08.057. Epub 2015 Sep 17. Cell. 2015. PMID: 26388442 Free PMC article.
Positive selection of tyrosine loss in metazoan evolution.
Tan CS, Pasculescu A, Lim WA, Pawson T, Bader GD, Linding R. Tan CS, et al. Among authors: linding r. Science. 2009 Sep 25;325(5948):1686-8. doi: 10.1126/science.1174301. Epub 2009 Jul 9. Science. 2009. PMID: 19589966 Free PMC article.
Personalized network-based treatments in oncology.
Robin X, Creixell P, Radetskaya O, Santini CC, Longden J, Linding R. Robin X, et al. Among authors: linding r. Clin Pharmacol Ther. 2013 Dec;94(6):646-50. doi: 10.1038/clpt.2013.171. Epub 2013 Aug 29. Clin Pharmacol Ther. 2013. PMID: 23995267 Review.
72 results