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Page 1
Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia.
Manoli I, Sysol JR, Li L, Houillier P, Garone C, Wang C, Zerfas PM, Cusmano-Ozog K, Young S, Trivedi NS, Cheng J, Sloan JL, Chandler RJ, Abu-Asab M, Tsokos M, Elkahloun AG, Rosen S, Enns GM, Berry GT, Hoffmann V, DiMauro S, Schnermann J, Venditti CP. Manoli I, et al. Among authors: rosen s. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13552-7. doi: 10.1073/pnas.1302764110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898205 Free PMC article. Clinical Trial.
Methylmalonic acidemia: a megamitochondrial disorder affecting the kidney.
Zsengellér ZK, Aljinovic N, Teot LA, Korson M, Rodig N, Sloan JL, Venditti CP, Berry GT, Rosen S. Zsengellér ZK, et al. Among authors: rosen s. Pediatr Nephrol. 2014 Nov;29(11):2139-46. doi: 10.1007/s00467-014-2847-y. Epub 2014 May 28. Pediatr Nephrol. 2014. PMID: 24865477
Beyond the tubule: pathological variants of LRP2, encoding the megalin receptor, result in glomerular loss and early progressive chronic kidney disease.
Charlton JR, Tan W, Daouk G, Teot L, Rosen S, Bennett KM, Cwiek A, Nam S, Emma F, Jouret F, Oliveira JP, Tranebjærg L, Frykholm C, Mane S, Hildebrandt F, Srivastava T, Storm T, Christensen EI, Nielsen R. Charlton JR, et al. Among authors: rosen s. Am J Physiol Renal Physiol. 2020 Dec 1;319(6):F988-F999. doi: 10.1152/ajprenal.00295.2020. Epub 2020 Oct 26. Am J Physiol Renal Physiol. 2020. PMID: 33103447 Free PMC article.
Normotensive ischemic acute renal failure.
Rosenberger C, Rosen S, Heyman SN. Rosenberger C, et al. Among authors: rosen s. N Engl J Med. 2007 Nov 22;357(21):2204-5; author reply 2205-6. doi: 10.1056/NEJMc072781. N Engl J Med. 2007. PMID: 18032776 No abstract available.
2,146 results