Almasan A - Search Results

1

The phosphatidylinositol 3-kinases (PI3K) inhibitor GS-1101 synergistically potentiates histone deacetylase inhibitor-induced proliferation inhibition and apoptosis through the inactivation of PI3K and extracellular signal-regulated kinase pathways.

Bodo J, Zhao X, Sharma A, Hill BT, Portell CA, Lannutti BJ, Almasan A, Hsi ED. Bodo J, et al. Among authors: almasan a. Br J Haematol. 2013 Oct;163(1):72-80. doi: 10.1111/bjh.12498. Epub 2013 Jul 25. Br J Haematol. 2013. PMID: 23889282 Free PMC article.

2

Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma.

Chen Q, Gong B, Mahmoud-Ahmed AS, Zhou A, Hsi ED, Hussein M, Almasan A. Chen Q, et al. Among authors: almasan a. Blood. 2001 Oct 1;98(7):2183-92. doi: 10.1182/blood.v98.7.2183. Blood. 2001. PMID: 11568006 Free PMC article.

3

HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells.

Bodo J, Sedlak J, Maciejewski JP, Almasan A, Hsi ED. Bodo J, et al. Among authors: almasan a. Apoptosis. 2011 Sep;16(9):914-23. doi: 10.1007/s10495-011-0617-x. Apoptosis. 2011. PMID: 21667043

4

An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737.

Al-Harbi S, Hill BT, Mazumder S, Singh K, Devecchio J, Choudhary G, Rybicki LA, Kalaycio M, Maciejewski JP, Houghton JA, Almasan A. Al-Harbi S, et al. Among authors: almasan a. Blood. 2011 Sep 29;118(13):3579-90. doi: 10.1182/blood-2011-03-340364. Epub 2011 Jul 19. Blood. 2011. PMID: 21772052 Free PMC article.

5

Histone H2AX phosphorylation: a marker for DNA damage.

Sharma A, Singh K, Almasan A. Sharma A, et al. Among authors: almasan a. Methods Mol Biol. 2012;920:613-26. doi: 10.1007/978-1-61779-998-3_40. Methods Mol Biol. 2012. PMID: 22941631

6

PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.

Chatterjee P, Choudhary GS, Sharma A, Singh K, Heston WD, Ciezki J, Klein EA, Almasan A. Chatterjee P, et al. Among authors: almasan a. PLoS One. 2013;8(4):e60408. doi: 10.1371/journal.pone.0060408. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565244 Free PMC article.

7

BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells.

Sharma A, Singh K, Mazumder S, Hill BT, Kalaycio M, Almasan A. Sharma A, et al. Among authors: almasan a. Cell Death Dis. 2013 May 16;4(5):e628. doi: 10.1038/cddis.2013.155. Cell Death Dis. 2013. PMID: 23681223 Free PMC article.

8

Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin).

Singh K, Sharma A, Mir MC, Drazba JA, Heston WD, Magi-Galluzzi C, Hansel D, Rubin BP, Klein EA, Almasan A. Singh K, et al. Among authors: almasan a. Mol Cancer. 2014 Mar 23;13:70. doi: 10.1186/1476-4598-13-70. Mol Cancer. 2014. PMID: 24655592 Free PMC article.

9

Targeting mTORC1-mediated metabolic addiction overcomes fludarabine resistance in malignant B cells.

Sharma A, Janocha AJ, Hill BT, Smith MR, Erzurum SC, Almasan A. Sharma A, et al. Among authors: almasan a. Mol Cancer Res. 2014 Sep;12(9):1205-15. doi: 10.1158/1541-7786.MCR-14-0124. Epub 2014 Jul 24. Mol Cancer Res. 2014. PMID: 25061101 Free PMC article.

10

MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.

Choudhary GS, Al-Harbi S, Mazumder S, Hill BT, Smith MR, Bodo J, Hsi ED, Almasan A. Choudhary GS, et al. Among authors: almasan a. Cell Death Dis. 2015 Jan 15;6(1):e1593. doi: 10.1038/cddis.2014.525. Cell Death Dis. 2015. PMID: 25590803 Free PMC article.

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