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In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating sodium channel slow inactivation.
Wang Y, Brittain JM, Jarecki BW, Park KD, Wilson SM, Wang B, Hale R, Meroueh SO, Cummins TR, Khanna R. Wang Y, et al. Among authors: khanna r. J Biol Chem. 2010 Aug 13;285(33):25296-307. doi: 10.1074/jbc.M110.128801. Epub 2010 Jun 9. J Biol Chem. 2010. PMID: 20538611 Free PMC article.
Effect of CRMP3 expression on dystrophic dendrites of hippocampal neurons.
Quach TT, Wang Y, Khanna R, Chounlamountri N, Auvergnon N, Honnorat J, Duchemin AM. Quach TT, et al. Among authors: khanna r. Mol Psychiatry. 2011 Jul;16(7):689-91. doi: 10.1038/mp.2011.6. Epub 2011 Feb 22. Mol Psychiatry. 2011. PMID: 21339751 No abstract available.
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex.
Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, Cheon BM, Due MR, Brustovetsky T, Ashpole NM, Hudmon A, Meroueh SO, Hingtgen CM, Brustovetsky N, Ji RR, Hurley JH, Jin X, Shekhar A, Xu XM, Oxford GS, Vasko MR, White FA, Khanna R. Brittain JM, et al. Among authors: khanna r, khanna m. Nat Med. 2011 Jun 5;17(7):822-9. doi: 10.1038/nm.2345. Nat Med. 2011. PMID: 21642979 Free PMC article.
Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex.
Wilson SM, Brittain JM, Piekarz AD, Ballard CJ, Ripsch MS, Cummins TR, Hurley JH, Khanna M, Hammes NM, Samuels BC, White FA, Khanna R. Wilson SM, et al. Among authors: khanna r, khanna m. Channels (Austin). 2011 Sep-Oct;5(5):449-56. doi: 10.4161/chan.5.5.17363. Epub 2011 Sep 1. Channels (Austin). 2011. PMID: 21829088 Free PMC article.
Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2).
Brittain JM, Chen L, Wilson SM, Brustovetsky T, Gao X, Ashpole NM, Molosh AI, You H, Hudmon A, Shekhar A, White FA, Zamponi GW, Brustovetsky N, Chen J, Khanna R. Brittain JM, et al. Among authors: khanna r. J Biol Chem. 2011 Oct 28;286(43):37778-92. doi: 10.1074/jbc.M111.255455. Epub 2011 Aug 9. J Biol Chem. 2011. PMID: 21832084 Free PMC article.
2,136 results