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Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model.
Arcaroli JJ, Quackenbush KS, Purkey A, Powell RW, Pitts TM, Bagby S, Tan AC, Cross B, McPhillips K, Song EK, Tai WM, Winn RA, Bikkavilli K, Vanscoyk M, Eckhardt SG, Messersmith WA. Arcaroli JJ, et al. Among authors: vanscoyk m. Br J Cancer. 2013 Aug 6;109(3):667-75. doi: 10.1038/bjc.2013.361. Epub 2013 Jul 18. Br J Cancer. 2013. PMID: 23868008 Free PMC article.
Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.
Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE. Winn RA, et al. J Biol Chem. 2005 May 20;280(20):19625-34. doi: 10.1074/jbc.M409392200. Epub 2005 Feb 10. J Biol Chem. 2005. PMID: 15705594 Free article.
Role of the wnt signaling pathway and lung cancer.
Tennis M, Van Scoyk M, Winn RA. Tennis M, et al. J Thorac Oncol. 2007 Oct;2(10):889-92. doi: 10.1097/JTO.0b013e318153fdb1. J Thorac Oncol. 2007. PMID: 17909349 Free article. Review. No abstract available.
Wnt signaling pathway and lung disease.
Van Scoyk M, Randall J, Sergew A, Williams LM, Tennis M, Winn RA. Van Scoyk M, et al. Transl Res. 2008 Apr;151(4):175-80. doi: 10.1016/j.trsl.2007.12.011. Epub 2008 Feb 5. Transl Res. 2008. PMID: 18355764 Review.
The role of prostacyclin in lung cancer.
Tennis MA, Vanscoyk M, Keith RL, Winn RA. Tennis MA, et al. Among authors: vanscoyk m. Transl Res. 2010 Feb;155(2):57-61. doi: 10.1016/j.trsl.2009.06.010. Epub 2009 Jul 23. Transl Res. 2010. PMID: 20129485
Dishevelled3 is a novel arginine methyl transferase substrate.
Bikkavilli RK, Avasarala S, Vanscoyk M, Sechler M, Kelley N, Malbon CC, Winn RA. Bikkavilli RK, et al. Among authors: vanscoyk m. Sci Rep. 2012;2:805. doi: 10.1038/srep00805. Epub 2012 Nov 13. Sci Rep. 2012. PMID: 23150776 Free PMC article.
26 results