Fang J - Search Results

1

In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures.

Jing Q, Li H, Fang J, Roman LJ, Martásek P, Poulos TL, Silverman RB. Jing Q, et al. Among authors: fang j. Bioorg Med Chem. 2013 Sep 1;21(17):5323-31. doi: 10.1016/j.bmc.2013.06.014. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23867386 Free PMC article.

2

Synthesis and evaluation of furo[3,4-d]pyrimidinones as selective alpha1a-adrenergic receptor antagonists.

Lagu B, Tian D, Chiu G, Nagarathnam D, Fang J, Shen Q, Forray C, Ransom RW, Chang RS, Vyas KP, Zhang K, Gluchowski C. Lagu B, et al. Among authors: fang j. Bioorg Med Chem Lett. 2000 Jan 17;10(2):175-8. doi: 10.1016/s0960-894x(99)00653-8. Bioorg Med Chem Lett. 2000. PMID: 10673105

3

Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.

Igarashi J, Li H, Jamal J, Ji H, Fang J, Lawton GR, Silverman RB, Poulos TL. Igarashi J, et al. Among authors: fang j. J Med Chem. 2009 Apr 9;52(7):2060-6. doi: 10.1021/jm900007a. J Med Chem. 2009. PMID: 19296678 Free PMC article.

4

A cellular model for screening neuronal nitric oxide synthase inhibitors.

Fang J, Silverman RB. Fang J, et al. Anal Biochem. 2009 Jul 1;390(1):74-8. doi: 10.1016/j.ab.2009.04.004. Epub 2009 Apr 9. Anal Biochem. 2009. PMID: 19362065 Free PMC article.

5

L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors.

Fang J, Ji H, Lawton GR, Xue F, Roman LJ, Silverman RB. Fang J, et al. J Med Chem. 2009 Jul 23;52(14):4533-7. doi: 10.1021/jm900380j. J Med Chem. 2009. PMID: 19537690 Free PMC article.

6

Potent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability.

Xue F, Fang J, Lewis WW, Martásek P, Roman LJ, Silverman RB. Xue F, et al. Among authors: fang j. Bioorg Med Chem Lett. 2010 Jan 15;20(2):554-7. doi: 10.1016/j.bmcl.2009.11.086. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 19963381 Free PMC article.

7

Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.

Delker SL, Ji H, Li H, Jamal J, Fang J, Xue F, Silverman RB, Poulos TL. Delker SL, et al. Among authors: fang j. J Am Chem Soc. 2010 Apr 21;132(15):5437-42. doi: 10.1021/ja910228a. J Am Chem Soc. 2010. PMID: 20337441 Free PMC article.

8

Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.

Xue F, Huang J, Ji H, Fang J, Li H, Martásek P, Roman LJ, Poulos TL, Silverman RB. Xue F, et al. Among authors: fang j. Bioorg Med Chem. 2010 Sep 1;18(17):6526-37. doi: 10.1016/j.bmc.2010.06.074. Epub 2010 Jul 1. Bioorg Med Chem. 2010. PMID: 20673724 Free PMC article.

9

Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase.

Xue F, Li H, Fang J, Roman LJ, Martásek P, Poulos TL, Silverman RB. Xue F, et al. Among authors: fang j. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6258-61. doi: 10.1016/j.bmcl.2010.08.096. Epub 2010 Aug 26. Bioorg Med Chem Lett. 2010. PMID: 20833542 Free PMC article.

10

Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase.

Xue F, Li H, Delker SL, Fang J, Martásek P, Roman LJ, Poulos TL, Silverman RB. Xue F, et al. Among authors: fang j. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. doi: 10.1021/ja106175q. J Am Chem Soc. 2010. PMID: 20843082 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

12,566 results

Search Page

Filters