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Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein.
Laine M, Jarva H, Seitsonen S, Haapasalo K, Lehtinen MJ, Lindeman N, Anderson DH, Johnson PT, Järvelä I, Jokiranta TS, Hageman GS, Immonen I, Meri S. Laine M, et al. Among authors: jokiranta ts. J Immunol. 2007 Mar 15;178(6):3831-6. doi: 10.4049/jimmunol.178.6.3831. J Immunol. 2007. PMID: 17339482 Free PMC article. Clinical Trial.
Acquisition of complement factor H is important for pathogenesis of Streptococcus pyogenes infections: evidence from bacterial in vitro survival and human genetic association.
Haapasalo K, Vuopio J, Syrjänen J, Suvilehto J, Massinen S, Karppelin M, Järvelä I, Meri S, Kere J, Jokiranta TS. Haapasalo K, et al. Among authors: jokiranta ts. J Immunol. 2012 Jan 1;188(1):426-35. doi: 10.4049/jimmunol.1102545. Epub 2011 Dec 2. J Immunol. 2012. PMID: 22140259
Microbes bind complement inhibitor factor H via a common site.
Meri T, Amdahl H, Lehtinen MJ, Hyvärinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A, Jokiranta TS. Meri T, et al. Among authors: jokiranta ts. PLoS Pathog. 2013;9(4):e1003308. doi: 10.1371/journal.ppat.1003308. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637600 Free PMC article.
100 results