Haapasalo K - Search Results

1

Staphylococcal Ecb protein and host complement regulator factor H enhance functions of each other in bacterial immune evasion.

Amdahl H, Jongerius I, Meri T, Pasanen T, Hyvärinen S, Haapasalo K, van Strijp JA, Rooijakkers SH, Jokiranta TS. Amdahl H, et al. Among authors: haapasalo k. J Immunol. 2013 Aug 15;191(4):1775-84. doi: 10.4049/jimmunol.1300638. Epub 2013 Jul 17. J Immunol. 2013. PMID: 23863906

2

Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein.

Laine M, Jarva H, Seitsonen S, Haapasalo K, Lehtinen MJ, Lindeman N, Anderson DH, Johnson PT, Järvelä I, Jokiranta TS, Hageman GS, Immonen I, Meri S. Laine M, et al. Among authors: haapasalo k. J Immunol. 2007 Mar 15;178(6):3831-6. doi: 10.4049/jimmunol.178.6.3831. J Immunol. 2007. PMID: 17339482 Free PMC article. Clinical Trial.

3

Complement factor H allotype 402H is associated with increased C3b opsonization and phagocytosis of Streptococcus pyogenes.

Haapasalo K, Jarva H, Siljander T, Tewodros W, Vuopio-Varkila J, Jokiranta TS. Haapasalo K, et al. Mol Microbiol. 2008 Nov;70(3):583-94. doi: 10.1111/j.1365-2958.2008.06347.x. Epub 2008 Jun 27. Mol Microbiol. 2008. PMID: 18627465 Free article.

4

Loa loa Microfilariae evade complement attack in vivo by acquiring regulatory proteins from host plasma.

Haapasalo K, Meri T, Jokiranta TS. Haapasalo K, et al. Infect Immun. 2009 Sep;77(9):3886-93. doi: 10.1128/IAI.01583-08. Epub 2009 Jun 15. Infect Immun. 2009. PMID: 19528206 Free PMC article.

5

Fatal babesiosis in man, Finland, 2004.

Haapasalo K, Suomalainen P, Sukura A, Siikamaki H, Jokiranta TS. Haapasalo K, et al. Emerg Infect Dis. 2010 Jul;16(7):1116-8. doi: 10.3201/eid1607.091905. Emerg Infect Dis. 2010. PMID: 20587183 Free PMC article.

6

Acquisition of complement factor H is important for pathogenesis of Streptococcus pyogenes infections: evidence from bacterial in vitro survival and human genetic association.

Haapasalo K, Vuopio J, Syrjänen J, Suvilehto J, Massinen S, Karppelin M, Järvelä I, Meri S, Kere J, Jokiranta TS. Haapasalo K, et al. J Immunol. 2012 Jan 1;188(1):426-35. doi: 10.4049/jimmunol.1102545. Epub 2011 Dec 2. J Immunol. 2012. PMID: 22140259

7

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

Haapasalo K, van Kessel K, Nissilä E, Metso J, Johansson T, Miettinen S, Varjosalo M, Kirveskari J, Kuusela P, Chroni A, Jauhiainen M, van Strijp J, Jokiranta TS. Haapasalo K, et al. J Biol Chem. 2015 Nov 27;290(48):28977-87. doi: 10.1074/jbc.M115.669226. Epub 2015 Oct 14. J Biol Chem. 2015. PMID: 26468283 Free PMC article.

8

Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria.

Amdahl H, Haapasalo K, Tan L, Meri T, Kuusela PI, van Strijp JA, Rooijakkers S, Jokiranta TS. Amdahl H, et al. Among authors: haapasalo k. PLoS One. 2017 Mar 8;12(3):e0172675. doi: 10.1371/journal.pone.0172675. eCollection 2017. PLoS One. 2017. PMID: 28273167 Free PMC article.

9

The Psoriasis Risk Allele HLA-C*06:02 Shows Evidence of Association with Chronic or Recurrent Streptococcal Tonsillitis.

Haapasalo K, Koskinen LLE, Suvilehto J, Jousilahti P, Wolin A, Suomela S, Trembath R, Barker J, Vuopio J, Kere J, Jokiranta TS, Saavalainen P. Haapasalo K, et al. Infect Immun. 2018 Sep 21;86(10):e00304-18. doi: 10.1128/IAI.00304-18. Print 2018 Oct. Infect Immun. 2018. PMID: 30037793 Free PMC article.

10

Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration.

Haapasalo K, Wollman AJM, de Haas CJC, van Kessel KPM, van Strijp JAG, Leake MC. Haapasalo K, et al. FASEB J. 2019 Mar;33(3):3807-3824. doi: 10.1096/fj.201801910R. Epub 2018 Dec 3. FASEB J. 2019. PMID: 30509126 Free PMC article.

This effect may free mobile receptors to amplify hyperinflammatory reactions in early stages of microbial infections and have implications for several other similar bicomponent toxins and the design of new antibiotics.-Haapasalo, K., Wollman, A. J. M., de Haas, C. J …

This effect may free mobile receptors to amplify hyperinflammatory reactions in early stages of microbial infections and have implications f …

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