Rowlands JC - Search Results

1

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.

Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS. Harrill JA, et al. Among authors: rowlands jc. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. Toxicol Appl Pharmacol. 2013. PMID: 23859880

2

Cross-species comparisons of transcriptomic alterations in human and rat primary hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Black MB, Budinsky RA, Dombkowski A, Cukovic D, LeCluyse EL, Ferguson SS, Thomas RS, Rowlands JC. Black MB, et al. Among authors: rowlands jc. Toxicol Sci. 2012 May;127(1):199-215. doi: 10.1093/toxsci/kfs069. Epub 2012 Feb 1. Toxicol Sci. 2012. PMID: 22298810

3

Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis.

Harrill JA, Parks BB, Wauthier E, Rowlands JC, Reid LM, Thomas RS. Harrill JA, et al. Among authors: rowlands jc. Hepatology. 2015 Feb;61(2):548-60. doi: 10.1002/hep.27547. Epub 2015 Jan 5. Hepatology. 2015. PMID: 25284723 Free PMC article.

4

The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor.

Becker RA, Patlewicz G, Simon TW, Rowlands JC, Budinsky RA. Becker RA, et al. Among authors: rowlands jc. Regul Toxicol Pharmacol. 2015 Oct;73(1):172-90. doi: 10.1016/j.yrtph.2015.06.015. Epub 2015 Jul 2. Regul Toxicol Pharmacol. 2015. PMID: 26145830 Free article.

5

Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Harrill JA, Layko D, Nyska A, Hukkanen RR, Manno RA, Grassetti A, Lawson M, Martin G, Budinsky RA, Rowlands JC, Thomas RS. Harrill JA, et al. Among authors: rowlands jc. J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. J Appl Toxicol. 2016. PMID: 26278112

6

Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Phadnis-Moghe AS, Chen W, Li J, Crawford RB, Bach A, D'Ingillo S, Kovalova N, Suarez-Martinez JE, Kaplan BL, Harrill JA, Budinsky R, Rowlands JC, Thomas RS, Kaminski NE. Phadnis-Moghe AS, et al. Among authors: rowlands jc. Toxicology. 2016 Aug 10;368-369:172-182. doi: 10.1016/j.tox.2016.08.019. Epub 2016 Aug 31. Toxicology. 2016. PMID: 27590929

7

Human and rat primary hepatocyte CYP1A1 and 1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 2,3,4,7,8-pentachlorodibenzofuran.

Budinsky RA, LeCluyse EL, Ferguson SS, Rowlands JC, Simon T. Budinsky RA, et al. Among authors: rowlands jc. Toxicol Sci. 2010 Nov;118(1):224-35. doi: 10.1093/toxsci/kfq238. Epub 2010 Aug 12. Toxicol Sci. 2010. PMID: 20705892

8

An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene.

Rowlands JC, Urban JD, Wikoff DS, Budinsky RA. Rowlands JC, et al. Drug Metab Pharmacokinet. 2011;26(4):431-9. doi: 10.2133/dmpk.dmpk-11-sc-013. Epub 2011 Apr 22. Drug Metab Pharmacokinet. 2011. PMID: 21512261 Free article.

9

Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene.

Urban JD, Budinsky RA, Rowlands JC. Urban JD, et al. Among authors: rowlands jc. Drug Metab Pharmacokinet. 2011;26(6):637-45. doi: 10.2133/dmpk.DMPK-11-SC-031. Epub 2011 Aug 9. Drug Metab Pharmacokinet. 2011. PMID: 21828933 Free article.

10

A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators.

Simon TW, Budinsky RA, Rowlands JC. Simon TW, et al. Among authors: rowlands jc. PLoS One. 2015 Jun 3;10(6):e0127952. doi: 10.1371/journal.pone.0127952. eCollection 2015. PLoS One. 2015. PMID: 26039703 Free PMC article.

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