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Structural characterization of antibody-responses from Zolgensma treatment provides the blueprint for the engineering of an AAV capsid suitable for redosing.
Mietzsch M, Nelson AR, Hsi J, Zachary J, Potts L, Chipman P, Ghanem M, Khandekar N, Alexander IE, Logan GJ, Huiskonen JT, McKenna R. Mietzsch M, et al. Among authors: hsi j. bioRxiv [Preprint]. 2024 May 3:2024.05.01.590489. doi: 10.1101/2024.05.01.590489. bioRxiv. 2024. PMID: 38746165 Free PMC article. Preprint.
Impact of universal chlorhexidine bathing with or without COVID-19 intensive training on staff and resident COVID-19 case rates in nursing homes.
Gussin GM, Singh RD, Gohil SK, Saavedra R, Tjoa TT, Nguyen KP, Pedroza R, Hsi JB, O'Brien K, Berman C, Park J, Hsi EA, Ghasemian K, Osalvo A, Chun S, Fonda E, Huang SS. Gussin GM, et al. Among authors: hsi jb. Infect Control Hosp Epidemiol. 2024 Jul;45(7):906-909. doi: 10.1017/ice.2024.30. Epub 2024 Mar 5. Infect Control Hosp Epidemiol. 2024. PMID: 38440877
Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy.
Logan GJ, Mietzsch M, Khandekar N, D'Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE. Logan GJ, et al. Among authors: hsi j. Mol Ther. 2023 Jul 5;31(7):1979-1993. doi: 10.1016/j.ymthe.2023.03.032. Epub 2023 Apr 3. Mol Ther. 2023. PMID: 37012705 Free PMC article.
Structural Study of Aavrh.10 Receptor and Antibody Interactions.
Mietzsch M, Yu JC, Hsi J, Chipman P, Broecker F, Fuming Z, Linhardt RJ, Seeberger PH, Heilbronn R, McKenna R, Agbandje-McKenna M. Mietzsch M, et al. Among authors: hsi j. J Virol. 2021 Nov 9;95(23):e0124921. doi: 10.1128/JVI.01249-21. Epub 2021 Sep 22. J Virol. 2021. PMID: 34549984 Free PMC article.
35 results