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Page 1
A comprehensive platform for highly multiplexed mammalian functional genetic screens.
Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, Cowley GS, Yang X, Grenier JK, Giaever G, Root DE, Moffat J, Nislow C. Ketela T, et al. Among authors: moffat j. BMC Genomics. 2011 May 6;12:213. doi: 10.1186/1471-2164-12-213. BMC Genomics. 2011. PMID: 21548937 Free PMC article.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JLY, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J. Marcotte R, et al. Among authors: moffat j. Cancer Discov. 2012 Feb;2(2):172-189. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29. Cancer Discov. 2012. PMID: 22585861 Free PMC article.
Miniature short hairpin RNA screens to characterize antiproliferative drugs.
Kittanakom S, Arnoldo A, Brown KR, Wallace I, Kunavisarut T, Torti D, Heisler LE, Surendra A, Moffat J, Giaever G, Nislow C. Kittanakom S, et al. Among authors: moffat j. G3 (Bethesda). 2013 Aug 7;3(8):1375-87. doi: 10.1534/g3.113.006437. G3 (Bethesda). 2013. PMID: 23797109 Free PMC article.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.
Vizeacoumar FJ, Arnold R, Vizeacoumar FS, Chandrashekhar M, Buzina A, Young JT, Kwan JH, Sayad A, Mero P, Lawo S, Tanaka H, Brown KR, Baryshnikova A, Mak AB, Fedyshyn Y, Wang Y, Brito GC, Kasimer D, Makhnevych T, Ketela T, Datti A, Babu M, Emili A, Pelletier L, Wrana J, Wainberg Z, Kim PM, Rottapel R, O'Brien CA, Andrews B, Boone C, Moffat J. Vizeacoumar FJ, et al. Among authors: moffat j. Mol Syst Biol. 2013 Oct 8;9:696. doi: 10.1038/msb.2013.54. Mol Syst Biol. 2013. PMID: 24104479 Free PMC article.
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
Petschnigg J, Groisman B, Kotlyar M, Taipale M, Zheng Y, Kurat CF, Sayad A, Sierra JR, Mattiazzi Usaj M, Snider J, Nachman A, Krykbaeva I, Tsao MS, Moffat J, Pawson T, Lindquist S, Jurisica I, Stagljar I. Petschnigg J, et al. Among authors: moffat j. Nat Methods. 2014 May;11(5):585-92. doi: 10.1038/nmeth.2895. Epub 2014 Mar 23. Nat Methods. 2014. PMID: 24658140
479 results