Lee HJ - Search Results

1

FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency.

Ficz G, Hore TA, Santos F, Lee HJ, Dean W, Arand J, Krueger F, Oxley D, Paul YL, Walter J, Cook SJ, Andrews S, Branco MR, Reik W. Ficz G, et al. Among authors: lee hj. Cell Stem Cell. 2013 Sep 5;13(3):351-9. doi: 10.1016/j.stem.2013.06.004. Epub 2013 Jul 11. Cell Stem Cell. 2013. PMID: 23850245 Free PMC article.

2

Reprogramming the methylome: erasing memory and creating diversity.

Lee HJ, Hore TA, Reik W. Lee HJ, et al. Cell Stem Cell. 2014 Jun 5;14(6):710-9. doi: 10.1016/j.stem.2014.05.008. Cell Stem Cell. 2014. PMID: 24905162 Free PMC article.

3

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ, Angermueller C, Smallwood SA, Krueger F, Mohammed H, Dean W, Nichols J, Rugg-Gunn P, Kelsey G, Stegle O, Simons BD, Reik W. Rulands S, et al. Among authors: lee hj. Cell Syst. 2018 Jul 25;7(1):63-76.e12. doi: 10.1016/j.cels.2018.06.012. Cell Syst. 2018. PMID: 30031774 Free PMC article.

4

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.

Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, Peat J, Andrews SR, Stegle O, Reik W, Kelsey G. Smallwood SA, et al. Among authors: lee hj. Nat Methods. 2014 Aug;11(8):817-820. doi: 10.1038/nmeth.3035. Epub 2014 Jul 20. Nat Methods. 2014. PMID: 25042786 Free PMC article.

5

Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).

Clark SJ, Smallwood SA, Lee HJ, Krueger F, Reik W, Kelsey G. Clark SJ, et al. Among authors: lee hj. Nat Protoc. 2017 Mar;12(3):534-547. doi: 10.1038/nprot.2016.187. Epub 2017 Feb 9. Nat Protoc. 2017. PMID: 28182018

6

Etoposide induces nuclear re-localisation of AID.

Lambert LJ, Walker S, Feltham J, Lee HJ, Reik W, Houseley J. Lambert LJ, et al. Among authors: lee hj. PLoS One. 2013 Dec 4;8(12):e82110. doi: 10.1371/journal.pone.0082110. eCollection 2013. PLoS One. 2013. PMID: 24324754 Free PMC article.

7

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.

Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Angermueller C, et al. Among authors: lee hj. Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11. Nat Methods. 2016. PMID: 26752769 Free PMC article.

8

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Clark SJ, Lee HJ, Smallwood SA, Kelsey G, Reik W. Clark SJ, et al. Among authors: lee hj. Genome Biol. 2016 Apr 18;17:72. doi: 10.1186/s13059-016-0944-x. Genome Biol. 2016. PMID: 27091476 Free PMC article. Review.

9

Tracking the embryonic stem cell transition from ground state pluripotency.

Kalkan T, Olova N, Roode M, Mulas C, Lee HJ, Nett I, Marks H, Walker R, Stunnenberg HG, Lilley KS, Nichols J, Reik W, Bertone P, Smith A. Kalkan T, et al. Among authors: lee hj. Development. 2017 Apr 1;144(7):1221-1234. doi: 10.1242/dev.142711. Epub 2017 Feb 7. Development. 2017. PMID: 28174249 Free PMC article.

10

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.

Clark SJ, Argelaguet R, Kapourani CA, Stubbs TM, Lee HJ, Alda-Catalinas C, Krueger F, Sanguinetti G, Kelsey G, Marioni JC, Stegle O, Reik W. Clark SJ, et al. Among authors: lee hj. Nat Commun. 2018 Feb 22;9(1):781. doi: 10.1038/s41467-018-03149-4. Nat Commun. 2018. PMID: 29472610 Free PMC article.

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