Van Aalten DM - Search Results

1

Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target.

Fang W, Du T, Raimi OG, Hurtado-Guerrero R, Mariño K, Ibrahim AF, Albarbarawi O, Ferguson MA, Jin C, Van Aalten DM. Fang W, et al. Among authors: van aalten dm. Biosci Rep. 2013 Sep 4;33(5):e00063. doi: 10.1042/BSR20130053. Biosci Rep. 2013. PMID: 23844980 Free PMC article.

2

The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.

Urbaniak MD, Crossman A, Chang T, Smith TK, van Aalten DM, Ferguson MA. Urbaniak MD, et al. Among authors: van aalten dm. J Biol Chem. 2005 Jun 17;280(24):22831-8. doi: 10.1074/jbc.M502402200. Epub 2005 Apr 6. J Biol Chem. 2005. PMID: 15817455 Free article.

3

An efficient synthesis of argifin: a natural product chitinase inhibitor with chemotherapeutic potential.

Dixon MJ, Andersen OA, van Aalten DM, Eggleston IM. Dixon MJ, et al. Among authors: van aalten dm. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4717-21. doi: 10.1016/j.bmcl.2005.07.068. Bioorg Med Chem Lett. 2005. PMID: 16153835

4

Structure of Saccharomyces cerevisiae chitinase 1 and screening-based discovery of potent inhibitors.

Hurtado-Guerrero R, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. Chem Biol. 2007 May;14(5):589-99. doi: 10.1016/j.chembiol.2007.03.015. Chem Biol. 2007. PMID: 17524989

5

Glucose-6-phosphate as a probe for the glucosamine-6-phosphate N-acetyltransferase Michaelis complex.

Hurtado-Guerrero R, Raimi O, Shepherd S, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. FEBS Lett. 2007 Dec 11;581(29):5597-600. doi: 10.1016/j.febslet.2007.10.065. Epub 2007 Nov 20. FEBS Lett. 2007. PMID: 18005663 Free article.

6

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.

Hurtado-Guerrero R, Raimi OG, Min J, Zeng H, Vallius L, Shepherd S, Ibrahim AF, Wu H, Plotnikov AN, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. Biochem J. 2008 Oct 15;415(2):217-23. doi: 10.1042/BJ20081000. Biochem J. 2008. PMID: 18601654

7

Structural insights into mechanism and specificity of O-GlcNAc transferase.

Clarke AJ, Hurtado-Guerrero R, Pathak S, Schüttelkopf AW, Borodkin V, Shepherd SM, Ibrahim AF, van Aalten DM. Clarke AJ, et al. Among authors: van aalten dm. EMBO J. 2008 Oct 22;27(20):2780-8. doi: 10.1038/emboj.2008.186. Epub 2008 Sep 25. EMBO J. 2008. PMID: 18818698 Free PMC article.

8

Molecular mechanisms of O-GlcNAcylation.

Hurtado-Guerrero R, Dorfmueller HC, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. Curr Opin Struct Biol. 2008 Oct;18(5):551-7. doi: 10.1016/j.sbi.2008.09.005. Epub 2008 Oct 6. Curr Opin Struct Biol. 2008. PMID: 18822376 Review.

9

Molecular mechanisms of yeast cell wall glucan remodeling.

Hurtado-Guerrero R, Schüttelkopf AW, Mouyna I, Ibrahim AF, Shepherd S, Fontaine T, Latgé JP, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. J Biol Chem. 2009 Mar 27;284(13):8461-9. doi: 10.1074/jbc.M807990200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097997 Free PMC article.

10

Structural and functional characterization of a putative polysaccharide deacetylase of the human parasite Encephalitozoon cuniculi.

Urch JE, Hurtado-Guerrero R, Brosson D, Liu Z, Eijsink VG, Texier C, van Aalten DM. Urch JE, et al. Among authors: van aalten dm. Protein Sci. 2009 Jun;18(6):1197-209. doi: 10.1002/pro.128. Protein Sci. 2009. PMID: 19472335 Free PMC article.

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