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Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.
Dituri F, Mazzocca A, Fernando J, Peidrò FJ, Papappicco P, Fabregat I, De Santis F, Paradiso A, Sabbà C, Giannelli G. Dituri F, et al. Among authors: fabregat i. PLoS One. 2013 Jun 27;8(6):e67109. doi: 10.1371/journal.pone.0067109. Print 2013. PLoS One. 2013. PMID: 23826206 Free PMC article.
TGF-beta signaling in cancer treatment.
Fabregat I, Fernando J, Mainez J, Sancho P. Fabregat I, et al. Curr Pharm Des. 2014;20(17):2934-47. doi: 10.2174/13816128113199990591. Curr Pharm Des. 2014. PMID: 23944366 Review.
A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells.
Fernando J, Malfettone A, Cepeda EB, Vilarrasa-Blasi R, Bertran E, Raimondi G, Fabra À, Alvarez-Barrientos A, Fernández-Salguero P, Fernández-Rodríguez CM, Giannelli G, Sancho P, Fabregat I. Fernando J, et al. Among authors: fabregat i. Int J Cancer. 2015 Feb 15;136(4):E161-72. doi: 10.1002/ijc.29097. Epub 2014 Aug 4. Int J Cancer. 2015. PMID: 25053293
TGF-β signalling and liver disease.
Fabregat I, Moreno-Càceres J, Sánchez A, Dooley S, Dewidar B, Giannelli G, Ten Dijke P; IT-LIVER Consortium. Fabregat I, et al. FEBS J. 2016 Jun;283(12):2219-32. doi: 10.1111/febs.13665. Epub 2016 Feb 22. FEBS J. 2016. PMID: 26807763 Free article. Review.
The rationale for targeting TGF-β in chronic liver diseases.
Giannelli G, Mikulits W, Dooley S, Fabregat I, Moustakas A, ten Dijke P, Portincasa P, Winter P, Janssen R, Leporatti S, Herrera B, Sanchez A. Giannelli G, et al. Among authors: fabregat i. Eur J Clin Invest. 2016 Apr;46(4):349-61. doi: 10.1111/eci.12596. Epub 2016 Mar 12. Eur J Clin Invest. 2016. PMID: 26823073 Review.
166 results