Leary DH - Search Results

1

3-substituted indole inhibitors against Francisella tularensis FabI identified by structure-based virtual screening.

Hu X, Compton JR, Abdulhameed MD, Marchand CL, Robertson KL, Leary DH, Jadhav A, Hershfield JR, Wallqvist A, Friedlander AM, Legler PM. Hu X, et al. Among authors: leary dh. J Med Chem. 2013 Jul 11;56(13):5275-87. doi: 10.1021/jm4001242. Epub 2013 Jul 1. J Med Chem. 2013. PMID: 23815100

2

A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: evidence for an oxidation sensitive motif.

Legler PM, Leary DH, Hervey WJ 4th, Millard CB. Legler PM, et al. Among authors: leary dh. Arch Biochem Biophys. 2012 Dec 1;528(1):7-20. doi: 10.1016/j.abb.2012.08.001. Epub 2012 Aug 13. Arch Biochem Biophys. 2012. PMID: 22906720

3

Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.

George J, Compton JR, Leary DH, Olson MA, Legler PM. George J, et al. Among authors: leary dh. Proteins. 2014 Nov;82(11):3101-16. doi: 10.1002/prot.24671. Epub 2014 Sep 11. Proteins. 2014. PMID: 25136772

4

A novel Vibrio beta-glucosidase (LamN) that hydrolyzes the algal storage polysaccharide laminarin.

Wang Z, Robertson KL, Liu C, Liu JL, Johnson BJ, Leary DH, Compton JR, Vuddhakul V, Legler PM, Vora GJ. Wang Z, et al. Among authors: leary dh. FEMS Microbiol Ecol. 2015 Aug;91(8):fiv087. doi: 10.1093/femsec/fiv087. Epub 2015 Jul 22. FEMS Microbiol Ecol. 2015. PMID: 26207048

5

Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease.

Hu X, Compton JR, Leary DH, Olson MA, Lee MS, Cheung J, Ye W, Ferrer M, Southall N, Jadhav A, Morazzani EM, Glass PJ, Marugan J, Legler PM. Hu X, et al. Among authors: leary dh. Biochemistry. 2016 May 31;55(21):3007-19. doi: 10.1021/acs.biochem.5b00992. Epub 2016 May 19. Biochemistry. 2016. PMID: 27030368 Free PMC article.

6

Proteolytic cleavage of host proteins by the Group IV viral proteases of Venezuelan equine encephalitis virus and Zika virus.

Morazzani EM, Compton JR, Leary DH, Berry AV, Hu X, Marugan JJ, Glass PJ, Legler PM. Morazzani EM, et al. Among authors: leary dh. Antiviral Res. 2019 Apr;164:106-122. doi: 10.1016/j.antiviral.2019.02.001. Epub 2019 Feb 10. Antiviral Res. 2019. PMID: 30742841 Free PMC article.

7

Codon harmonization reduces amino acid misincorporation in bacterially expressed P. falciparum proteins and improves their immunogenicity.

Punde N, Kooken J, Leary D, Legler PM, Angov E. Punde N, et al. AMB Express. 2019 Oct 19;9(1):167. doi: 10.1186/s13568-019-0890-6. AMB Express. 2019. PMID: 31630257 Free PMC article.

8

Melanin Produced by the Fast-Growing Marine Bacterium Vibrio natriegens through Heterologous Biosynthesis: Characterization and Application.

Wang Z, Tschirhart T, Schultzhaus Z, Kelly EE, Chen A, Oh E, Nag O, Glaser ER, Kim E, Lloyd PF, Charles PT, Li W, Leary D, Compton J, Phillips DA, Dhinojwala A, Payne GF, Vora GJ. Wang Z, et al. Appl Environ Microbiol. 2020 Feb 18;86(5):e02749-19. doi: 10.1128/AEM.02749-19. Print 2020 Feb 18. Appl Environ Microbiol. 2020. PMID: 31836580 Free PMC article.

9

The SARS-CoV-2 SSHHPS Recognized by the Papain-like Protease.

Reynolds ND, Aceves NM, Liu JL, Compton JR, Leary DH, Freitas BT, Pegan SD, Doctor KZ, Wu FY, Hu X, Legler PM. Reynolds ND, et al. Among authors: leary dh. ACS Infect Dis. 2021 Jun 11;7(6):1483-1502. doi: 10.1021/acsinfecdis.0c00866. Epub 2021 May 21. ACS Infect Dis. 2021. PMID: 34019767 Free PMC article.

10

Vibrio natriegens genome-scale modeling reveals insights into halophilic adaptations and resource allocation.

Coppens L, Tschirhart T, Leary DH, Colston SM, Compton JR, Hervey WJ 4th, Dana KL, Vora GJ, Bordel S, Ledesma-Amaro R. Coppens L, et al. Among authors: leary dh. Mol Syst Biol. 2023 Apr 12;19(4):e10523. doi: 10.15252/msb.202110523. Epub 2023 Feb 27. Mol Syst Biol. 2023. PMID: 36847213 Free PMC article.

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