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Page 1
Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.
Fumagalli L, Pallavicini M, Budriesi R, Gobbi M, Straniero V, Zagami M, Chiodini G, Bolchi C, Chiarini A, Micucci M, Valoti E. Fumagalli L, et al. Among authors: straniero v. Eur J Med Chem. 2012 Dec;58:184-91. doi: 10.1016/j.ejmech.2012.09.049. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124215
6-methoxy-7-benzofuranoxy and 6-methoxy-7-indolyloxy analogues of 2-[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4-benzodioxane (WB4101):1 discovery of a potent and selective α1D-adrenoceptor antagonist.
Fumagalli L, Pallavicini M, Budriesi R, Bolchi C, Canovi M, Chiarini A, Chiodini G, Gobbi M, Laurino P, Micucci M, Straniero V, Valoti E. Fumagalli L, et al. Among authors: straniero v. J Med Chem. 2013 Aug 22;56(16):6402-12. doi: 10.1021/jm400867d. Epub 2013 Jul 31. J Med Chem. 2013. PMID: 23902232
Benzodioxane-benzamides as new bacterial cell division inhibitors.
Chiodini G, Pallavicini M, Zanotto C, Bissa M, Radaelli A, Straniero V, Bolchi C, Fumagalli L, Ruggeri P, De Giuli Morghen C, Valoti E. Chiodini G, et al. Among authors: straniero v. Eur J Med Chem. 2015 Jan 7;89:252-65. doi: 10.1016/j.ejmech.2014.09.100. Epub 2014 Oct 18. Eur J Med Chem. 2015. PMID: 25462242
3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division.
Straniero V, Pallavicini M, Chiodini G, Zanotto C, Volontè L, Radaelli A, Bolchi C, Fumagalli L, Sanguinetti M, Menchinelli G, Delogu G, Battah B, De Giuli Morghen C, Valoti E. Straniero V, et al. Eur J Med Chem. 2016 Sep 14;120:227-43. doi: 10.1016/j.ejmech.2016.03.068. Epub 2016 Mar 28. Eur J Med Chem. 2016. PMID: 27191617
30 results