Schofield CJ - Search Results

1

Is JmjC oxygenase catalysis limited to demethylation?

Hopkinson RJ, Walport LJ, Münzel M, Rose NR, Smart TJ, Kawamura A, Claridge TD, Schofield CJ. Hopkinson RJ, et al. Among authors: schofield cj. Angew Chem Int Ed Engl. 2013 Jul 22;52(30):7709-13. doi: 10.1002/anie.201303282. Epub 2013 Jun 20. Angew Chem Int Ed Engl. 2013. PMID: 23788451 Free PMC article.

2

Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides.

Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Baldwin JE, et al. Among authors: schofield cj. Int J Pept Protein Res. 1994 Feb;43(2):180-3. doi: 10.1111/j.1399-3011.1994.tb00520.x. Int J Pept Protein Res. 1994. PMID: 8200737

3

Oxidative degradation of bilirubin produces vasoactive compounds.

Kranc KR, Pyne GJ, Tao L, Claridge TD, Harris DA, Cadoux-Hudson TA, Turnbull JJ, Schofield CJ, Clark JF. Kranc KR, et al. Among authors: schofield cj. Eur J Biochem. 2000 Dec;267(24):7094-101. doi: 10.1046/j.1432-1327.2000.01812.x. Eur J Biochem. 2000. PMID: 11106420 Free article.

4

Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.

Kershaw NJ, Mukherji M, MacKinnon CH, Claridge TD, Odell B, Wierzbicki AS, Lloyd MD, Schofield CJ. Kershaw NJ, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2545-8. doi: 10.1016/s0960-894x(01)00494-2. Bioorg Med Chem Lett. 2001. PMID: 11549466

5

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

Hon WC, Wilson MI, Harlos K, Claridge TD, Schofield CJ, Pugh CW, Maxwell PH, Ratcliffe PJ, Stuart DI, Jones EY. Hon WC, et al. Among authors: schofield cj. Nature. 2002 Jun 27;417(6892):975-8. doi: 10.1038/nature00767. Epub 2002 Jun 5. Nature. 2002. PMID: 12050673

6

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.

McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE, Schofield CJ. McNeill LA, et al. Among authors: schofield cj. Biochem J. 2002 Nov 1;367(Pt 3):571-5. doi: 10.1042/BJ20021162. Biochem J. 2002. PMID: 12215170 Free PMC article.

7

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.

Welford RW, Turnbull JJ, Claridge TD, Prescott AG, Schofield CJ. Welford RW, et al. Among authors: schofield cj. Chem Commun (Camb). 2001 Sep 21;(18):1828-9. doi: 10.1039/b105576n. Chem Commun (Camb). 2001. PMID: 12240335

8

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate.

McNeill LA, Flashman E, Buck MR, Hewitson KS, Clifton IJ, Jeschke G, Claridge TD, Ehrismann D, Oldham NJ, Schofield CJ. McNeill LA, et al. Among authors: schofield cj. Mol Biosyst. 2005 Oct;1(4):321-4. doi: 10.1039/b511249b. Epub 2005 Aug 22. Mol Biosyst. 2005. PMID: 16880998

9

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U. Ng SS, et al. Among authors: schofield cj. Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24. Nature. 2007. PMID: 17589501

10

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.

Rose NR, Ng SS, Mecinović J, Liénard BM, Bello SH, Sun Z, McDonough MA, Oppermann U, Schofield CJ. Rose NR, et al. Among authors: schofield cj. J Med Chem. 2008 Nov 27;51(22):7053-6. doi: 10.1021/jm800936s. J Med Chem. 2008. PMID: 18942826

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