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Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).
Jaiswal M, Gremer L, Dvorsky R, Haeusler LC, Cirstea IC, Uhlenbrock K, Ahmadian MR. Jaiswal M, et al. Among authors: gremer l. J Biol Chem. 2011 May 20;286(20):18202-12. doi: 10.1074/jbc.M111.226431. Epub 2011 Mar 28. J Biol Chem. 2011. PMID: 21454492 Free PMC article.
Biochemical assays to characterize Rho GTPases.
Jaiswal M, Dubey BN, Koessmeier KT, Gremer L, Ahmadian MR. Jaiswal M, et al. Among authors: gremer l. Methods Mol Biol. 2012;827:37-58. doi: 10.1007/978-1-61779-442-1_3. Methods Mol Biol. 2012. PMID: 22144266
Rho-kinase: regulation, (dys)function, and inhibition.
Amin E, Dubey BN, Zhang SC, Gremer L, Dvorsky R, Moll JM, Taha MS, Nagel-Steger L, Piekorz RP, Somlyo AV, Ahmadian MR. Amin E, et al. Among authors: gremer l. Biol Chem. 2013 Nov;394(11):1399-410. doi: 10.1515/hsz-2013-0181. Biol Chem. 2013. PMID: 23950574 Free PMC article. Review.
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.
Thakur HC, Singh M, Nagel-Steger L, Kremer J, Prumbaum D, Fansa EK, Ezzahoini H, Nouri K, Gremer L, Abts A, Schmitt L, Raunser S, Ahmadian MR, Piekorz RP. Thakur HC, et al. Among authors: gremer l. J Biol Chem. 2014 Jan 3;289(1):74-88. doi: 10.1074/jbc.M113.532333. Epub 2013 Nov 22. J Biol Chem. 2014. PMID: 24273164 Free PMC article.
78 results